Protocol - Diabetic Peripheral Neuropathy
- Gender Identity
- Height - Knee Height
- Personal History of Type I and Type II Diabetes
- Sex Assigned at Birth
Description
The Michigan Neuropathy Screening Instrument (MNSI) consists of 15 yes-or-no questions that assess feelings in the legs and feet (distal symmetric polyneuropathy). The MNSI also includes a clinical examination that is not included here.
Specific Instructions
None
Availability
Protocol
Please take a few minutes to answer the questions below about the feeling in your legs and feet. Check yes or no based on how you usually feel.
1. Are your legs and/or feet numb?
[ ] Yes
[ ] No
2. Do you ever have any burning pain in your legs and/or feet?
[ ] Yes
[ ] No
3. Are your feet too sensitive to touch?
[ ] Yes
[ ] No
4. Do you get muscle cramps in your legs and/or feet?
[ ] Yes
[ ] No
5. Do you ever have any prickling feelings in your legs or feet?
[ ] Yes
[ ] No
6. Does it hurt when the bed covers touch your skin?
[ ] Yes
[ ] No
7. When you get into the tub or shower, are you able to tell the hot water from the cold water?
[ ] Yes
[ ] No
8. Have you ever had an open sore on your foot?
[ ] Yes
[ ] No
9. Has your doctor ever told you that you have diabetic neuropathy?
[ ] Yes
[ ] No
10. Do you feel weak all over most of the time?
[ ] Yes
[ ] No
11. Are your symptoms worse at night?
[ ] Yes
[ ] No
12. Do your legs hurt when you walk?
[ ] Yes
[ ] No
13. Are you able to sense your feet when you walk?
[ ] Yes
[ ] No
14. Is the skin on your feet so dry that it cracks open?
[ ] Yes
[ ] No
15. Have you ever had an amputation?
[ ] Yes
[ ] No
Total:______/15pts
Scoring Instructions:
Score each positive response as a "1". The greater the score, the greater risk for neuropathy.
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult, Senior
Participants
Participant aged 18 years or older.
Selection Rationale
The Michigan Neuropathy Screening Instrument (MNSI) was vetted against several other neuropathy protocols and chosen because it is a relatively well validated, widely used instrument.
Language
Chinese, English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| Logical Observation Identifiers Names and Codes (LOINC) | Diabetic peripheral neuropathy proto | 62795-0 | LOINC |
| Human Phenotype Ontology | Peripheral Neuropathy | HP:0009830 | HPO |
| caDSR Form | PhenX PX140401 - Diabetic Peripheral Neuropathy | 6257439 | caDSR Form |
Derived Variables
None
Process and Review
The Expert Review Panel #1 reviewed the measures in the Anthropometrics, Diabetes, Physical Activity and Physical Fitness, and Nutrition and Dietary Supplements domains.
Guidance from the ERP includes:
- No significant changes
Back-compatible: no changes to Data Dictionary
Previous version in Toolkit archive (link)
Protocol Name from Source
The Michigan Neuropathy Screening Instrument (MNSI)
Source
Feldman, EL, Stevens, MJ, Thomas, PK, Brown, MB, Canal, N & Greene, DA. (1994). A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care, 17(11), 1281-1289.
General References
American Diabetes Association (ADA). (2014). Standards of medical care in Diabetes-2014. Diabetes Care, 37 (Suppl. 1), S14 - S80.
Protocol ID
140401
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX140401_Amputation | ||||
| PX140401150000 | Have you ever had an amputation? | N/A | ||
| PX140401_Bed_Covers_Hurt | ||||
| PX140401060000 | Does it hurt when the bed covers touch your skin? | Variable Mapping | ||
| PX140401_Burning_Pain | ||||
| PX140401020000 | Do you ever have any burning pain in your more | Variable Mapping | ||
| PX140401_Diagnosed_Diabetic_Neuropathy | ||||
| PX140401090000 | Has your doctor ever told you that you have more | Variable Mapping | ||
| PX140401_Feel_Weak_All_Over | ||||
| PX140401100000 | Do you feel weak all over most of the time? | Variable Mapping | ||
| PX140401_Feet_Too_Sensitive_To_Touch | ||||
| PX140401030000 | Are your feet too sensitive to touch? | Variable Mapping | ||
| PX140401_Legs_Feet_Numb | ||||
| PX140401010000 | Are your legs and/or feet numb? | Variable Mapping | ||
| PX140401_Leg_Hurt_When_Walk | ||||
| PX140401120000 | Do your legs hurt when you walk? | Variable Mapping | ||
| PX140401_Muscle_Cramps | ||||
| PX140401040000 | Do you get muscle cramps in your legs and/or feet? | Variable Mapping | ||
| PX140401_Open_Sore | ||||
| PX140401080000 | Have you ever had an open sore on your foot? | Variable Mapping | ||
| PX140401_Prickling_Feelings | ||||
| PX140401050000 | Do you ever have any prickling feelings in more | Variable Mapping | ||
| PX140401_Sense_Feet_When_Walking | ||||
| PX140401130000 | Are you able to sense your feet when you walk? | Variable Mapping | ||
| PX140401_Skin_Cracks_Open | ||||
| PX140401140000 | Is the skin on your feet so dry that it more | Variable Mapping | ||
| PX140401_Symptoms_Worse_At_Night | ||||
| PX140401110000 | Are your symptoms worse at night? | Variable Mapping | ||
| PX140401_Tell_Hot_Water_From_Cold | ||||
| PX140401070000 | When you get into the tub or shower, are you more | Variable Mapping | ||
Measure Name
Diabetic Peripheral Neuropathy
Release Date
May 10, 2010
Definition
A questionnaire to determine if a respondent has a history of peripheral neuropathy.
Purpose
Diabetic peripheral neuropathy, also known as distal symmetric polyneuropathy, is a leading complication of both type 1 and type 2 diabetes and is responsible for more than half of all non-traumatic foot amputations in the United States. Incidence of distal symmetric polyneuropathy increases with diabetes duration with up to 50% of those with diabetes having the disease after 25 years (Feldman et al., 1994).
Keywords
diabetes, polyneuropathy, nerve disease
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 140401 | Diabetic Peripheral Neuropathy |
Publications
There are no publications listed for this protocol.