Protocol - Hand Dominance - 12 Years and Older

Description

The protocol consists of questions to determine which hand the participant uses for a series of activities.

Specific Instructions

None

Availability

Protocol

The following protocol is part of a personal interview in which the participant reports on his/her own hand usage. Young Adult and Adult handedness is assessed using an 11-item scale. Please indicate your preferences in the use of hands in the following activities by putting a 1 in the appropriate column (for right only, left only, or both hands) for each item that you use.

	Right hand	Left hand	Both hands
1. Write
2. Draw
3. Throw
4. Hold a racquet
5. Clean teeth
6. Hammer
7. Strike a match
8. Use an eraser
9. Deal cards
10. Thread a needle
11. Cut food with a knife
Total

Scoring: The participant indicates use by a "1" in the appropriate column (for right, left, or both) for each item that an adult uses. Add the "1"s in each column to get a total for that column. The sum of all three column totals is the cumulative total. To calculate the score: 100 x (right total - left total)/cumulative total. Handedness is then classified as follows:

Scoring:

Less than -40	left-handed
Greater than or equal to -40 and less than 40	mixed-handed
Greater than or equal to 40	right-handed

Note: The activities listed in the Edinburgh Handedness Inventory method have been modified by the PhenX Anthropometrics Working Group.

Personnel and Training Required

The trained interviewer should be able to administer a questionnaire and be able to probe for information as necessary.

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self- or proxy-reported value

Lifestage

Adolescent, Adult, Senior

Participants

This measure includes two protocols, each relating to a specific age of the participant. Consistent hand dominance starts to develop between 2 and 3 years of age and is usually completed by 6 years of age. Hand preference that appears before the age of 18 months may signal impaired neurological control of the other hand.

Avon Longitudinal Study of Parents and Children Protocol (ALSPAC)
Child beginning at 42 months of age

Edinburgh Handedness Inventory
Participant aged 12 years and older

Selection Rationale

The Edinburgh Handedness Inventory was selected because of the detail of the activities that are performed.

Language

Chinese, English

Standards

Standard	Name	ID	Source
Logical Observation Identifiers Names and Codes (LOINC)	Hand dom- 12Y proto EHI	56101-9	LOINC
Human Phenotype Ontology	Laterality	HP:0012831	HPO
caDSR Form	PhenX PX020602 - Hand Dominance 12 Years And Older	5801050	caDSR Form

Derived Variables

None

Process and Review

The Expert Review Panel #1 reviewed the measures in the Anthropometrics, Diabetes, Physical Activity and Physical Fitness, and Nutrition and Dietary Supplements domains.

Guidance from the ERP includes:

• Revised description of measure

Back-compatible: no changes to Data Dictionary

Previous version in Toolkit archive (link)

Protocol Name from Source

Edinburgh Handedness Inventory

Source

Oldfield, R. C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113.

General References

Porac, C., & Coren, S. (1981). Lateral preferences and human behavior. New York: Springer-Verlag.

Protocol ID

20602

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX020602_Handedness
	PX020602120500	Handedness is classified by the score.	Variable Mapping
PX020602_Handedness_Score
	PX020602120400	SCORE = 100 x (TOTAL_RIGHT - TOTAL_LEFT) / more (TOTAL_RIGHT + TOTAL_LEFT + TOTAL_BOTH) show less	N/A
PX020602_Hand_Clean_Teeth
	PX020602050000	Please indicate your preferences in the use more of hands in cleaning teeth. show less	Variable Mapping
PX020602_Hand_Cut_Food
	PX020602110000	Please indicate your preferences in the use more of hands in cutting food with a knife. show less	Variable Mapping
PX020602_Hand_Deal_Card
	PX020602090000	Please indicate your preferences in the use more of hands in dealing cards. show less	Variable Mapping
PX020602_Hand_Draw
	PX020602020000	Please indicate your preferences in the use more of hands in drawing. show less	Variable Mapping
PX020602_Hand_Hammer
	PX020602060000	Please indicate your preferences in the use more of hands in hammering. show less	Variable Mapping
PX020602_Hand_Hold_Racquet
	PX020602040000	Please indicate your preferences in the use more of hands in holding a racquet. show less	Variable Mapping
PX020602_Hand_Strike_Match
	PX020602070000	Please indicate your preferences in the use more of hands in striking a match. show less	Variable Mapping
PX020602_Hand_Thread_Needle
	PX020602100000	Please indicate your preferences in the use more of hands in threading a needle. show less	Variable Mapping
PX020602_Hand_Throw
	PX020602030000	Please indicate your preferences in the use more of hands in throwing. show less	Variable Mapping
PX020602_Hand_Total_Both
	PX020602120300	How many Both hands in Questions 1-11?	N/A
PX020602_Hand_Total_Left
	PX020602120200	How many Left hand in Questions 1-11?	N/A
PX020602_Hand_Total_Right
	PX020602120100	How many Right hand in Questions 1-11?	N/A
PX020602_Hand_Use_Eraser
	PX020602080000	Please indicate your preferences in the use more of hands in using an eraser. show less	Variable Mapping
PX020602_Hand_Write
	PX020602010000	Please indicate your preferences in the use more of hands in writing. show less	Variable Mapping

Anthropometrics

Measure Name

Hand Dominance

Release Date

March 27, 2009

Definition

Dominance is measured to assess the movement, mobility, and flexibility of an individual to determine which side of the body the study subject favors or the strength of hand activity.

Purpose

This measure is used to determine which hand is dominant or more skilled for fine motor tasks than the other. Of the general population, about 90% have right hand dominance, about 10% have left hand dominance, and about 1% are mixed-handed or can use either hand interchangeably to complete a fine motor task (Porac & Coren, 1981). Hand dominance is thought to be influenced by genetics, and loci for relative hand skill have been mapped.

Keywords

Anthropometrics, dominance, handedness, ambidextrous, ALSPAC

Measure Protocols

Protocol ID	Protocol Name
20601	Hand Dominance - 42 Months and Older
20602	Hand Dominance - 12 Years and Older

Publications

Schettini, E., et al. (2021) Internalizing-externalizing comorbidity and regional brain volumes in the ABCD study. Development and Psychopathology. 2021 December; 33(5): 1620-1633.

Barch, D. M., et al. (2021) Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories. Developmental Cognitive Neuroscience. 2021 December; 52: 101031. doi: 10.1016/j.dcn.2021.101031

Barch, D. M., et al. (2018) Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: Rationale and description. Dev Cogn Neurosci. 2018 August; 32: 55-66. doi: 10.1016/j.dcn.2017.10.010

Aris, I. M., et al. (2017) Postnatal height and adiposity gain, childhood blood pressure and prehypertension risk in an Asian birth cohort. Int J Obes (Lond). 2017 July; 41(7): 1011-1017. doi: 10.1038/ijo.2017.40

Aris, I. M., et al. (2016) MC3R gene polymorphisms are associated with early childhood adiposity gain and infant appetite in an Asian population. Pediatr Obes. 2016 December; 11(6): 450-458. doi: 10.1111/ijpo.12086

Chen, L. W., et al. (2016) Associations of Maternal Dietary Patterns during Pregnancy with Offspring Adiposity from Birth Until 54 Months of Age. Nutrients. 2016 December; 9(1): E2. doi: 10.3390/nu9010002

Mapping for PX020602_Handedness

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Atherosclerosis Risk in Communities (ARIC) Cohort	phv00207154	[Handedness]. Are you right-handed or left-handed? Q73 [Health/Medical History, exam 2]
CIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)	phv00045296	The subject has a hand preference (left, right), or uses both hands equally well (ambidextrous) (see phs000004: NINDS Repository Neurologically Normal Control Collection).
Coenzyme Q10 (CoQ) in Huntington's Disease (HD) (2CARE)	phv00261299	16 Handedness
GWAS on Cataract and HDL in the PMRP	phv00181826	Handedness Classification 1=Right 2=Left 3=Mixed
Ischemic Stroke Genetics Study (ISGS)	phv00024322	The subject has a hand preference (left, right), or uses both hands equally well (ambidextrous).
NIH Exome Sequencing of Familial Amyotrophic Lateral Sclerosis Project	phv00024145	The hand preference of the subject; the subject's dominant hand.
NIH Exome Sequencing of Familial Amyotrophic Lateral Sclerosis Project	phv00024219	The subject has a hand preference (left, right), or uses both hands equally well (ambidextrous).
NINDS Parkinson's Disease	phv00023996	Optional data: handedness (right, left, ambidextrous)
NINDS Parkinson's Disease	phv00024015	Handedness (right, left, ambidextrous)
NINDS Parkinsonism Study	phv00000190	The hand preference of the subject; the subject's dominant hand
NINDS Repository Cerebrovascular Disease/Stroke Study	phv00000297	The subject has a hand preference (left, right) or uses both hands equally well (ambidextrous).
NINDS Repository Motor Neuron Disease/ALS Study	phv00000405	The hand preference of the subject; the subject's dominant hand.
NINDS Repository Neurologically Normal Control Collection	phv00000272	The subject has a hand preference (left, right), or uses both hands equally well (ambidextrous).
Whole Exome Sequencing in Familial Parkinson Disease	phv00161346	Subject's report of handedness

Mapping for PX020602_Hand_Clean_Teeth

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Cardiovascular Health Study (CHS) Cohort	phv00104537	HAND USED TO BRUSH TEETH
Cardiovascular Health Study (CHS) Cohort	phv00105733	HAND USED TO BRUSH TEETH
Cardiovascular Health Study (CHS) Cohort	phv00106912	HAND USED TO BRUSH TEETH
Cardiovascular Health Study (CHS) Cohort	phv00107585	HAND USED TO BRUSH TEETH
Cardiovascular Health Study (CHS) Cohort	phv00108385	HAND USED TO BRUSH TEETH
GWAS on Cataract and HDL in the PMRP	phv00181513	Please indicate your preferences in the use of hands in cleaning teeth.
Women's Health Initiative	phv00079301	Hand used to hold a toothbrush

Mapping for PX020602_Hand_Cut_Food

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181519	Please indicate your preferences in the use of hands in cutting food with a knife.

Mapping for PX020602_Hand_Deal_Card

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181517	Please indicate your preferences in the use of hands in dealing cards.

Mapping for PX020602_Hand_Draw

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181510	Please indicate your preferences in the use of hands in drawing

Mapping for PX020602_Hand_Hammer

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181514	Please indicate your preferences in the use of hands in hammering.

Mapping for PX020602_Hand_Hold_Racquet

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181512	Please indicate your preferences in the use of hands in holding a racquet.

Mapping for PX020602_Hand_Strike_Match

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181515	Please indicate your preferences in the use of hands in striking a match.

Mapping for PX020602_Hand_Thread_Needle

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181518	Please indicate your preferences in the use of hands in threading a needle.

Mapping for PX020602_Hand_Throw

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Cardiovascular Health Study (CHS) Cohort	phv00104480	HAND USED TO THROW A BALL
Cardiovascular Health Study (CHS) Cohort	phv00105673	HAND USED TO THROW A BALL
Cardiovascular Health Study (CHS) Cohort	phv00106853	HAND USED TO THROW A BALL
Cardiovascular Health Study (CHS) Cohort	phv00107515	HAND USED TO THROW A BALL
Cardiovascular Health Study (CHS) Cohort	phv00108315	HAND USED TO THROW A BALL
GWAS on Cataract and HDL in the PMRP	phv00181511	Please indicate your preferences in the use of hands in throwing.
Women's Health Initiative	phv00079300	Hand used to throw a ball

Mapping for PX020602_Hand_Use_Eraser

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GWAS on Cataract and HDL in the PMRP	phv00181516	Please indicate your preferences in the use of hands in using an eraser.

Mapping for PX020602_Hand_Write

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Cardiovascular Health Study (CHS) Cohort	phv00109852	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00109140	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00108389	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00101402	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00102280	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00103853	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00104541	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00105737	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00106916	WHICH HAND USED TO WRITE
Cardiovascular Health Study (CHS) Cohort	phv00107589	WHICH HAND USED TO WRITE
DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes	phv00031527	Patient's writing hand
Framingham Cohort	phv00251069	Numerical Data - Part I - Regional Anthropometry: Hand preferred for writing
Framingham Cohort	phv00003759	HAND USED TO WRITE NOW
Framingham Cohort	phv00021238	HAND PREFERED FOR WRITING
Framingham Cohort	phv00010506	REGIONAL ANTHROPOMETRY - HAND PREFERRED FOR WRITING
Framingham Cohort	phv00010121	HAND PREFERRED FOR WRITING
Genes and Blood Clotting Study (GABC)	phv00124405	With which hand do you write best?
GWAS on Cataract and HDL in the PMRP	phv00181509	Please indicate your preferences in the use of hands in writing.
Women's Health Initiative	phv00079286	Hand participant uses to write

Protocol - Hand Dominance - 12 Years and Older

Related Protocols:

Essential Protocols:

Studies Using This Protocol:

Description

Specific Instructions

Availability

Protocol

Personnel and Training Required

Equipment Needs

Requirements

Mode of Administration

Lifestage

Participants

Selection Rationale

Language

Standards

Derived Variables

Process and Review

Protocol Name from Source

Source

General References

Protocol ID

Variables

Measure Name

Release Date

Definition

Purpose

Keywords

Measure Protocols

Publications