Protocol - Serial Pregnancy Weight - Weights Measured During Gestation

Description

Serial measures of weight either (1) abstracted from health care (prenatal) records, or (2) measured prospectively for the duration of gestation. Data collected entail (1) weights measured at all prenatal visits; (2) dates of all prenatal visits; (3) reported pre-pregnancy weight; (4) reported or measured height; and (5) gestational age at every prenatal visit and at delivery. If the opportunity exists to collect the information prospectively as part of the research protocol, this is preferred.

Specific Instructions

None

Availability

Available

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Protocol

Weights Measured during Gestation (Research Protocol)

Gestational ages, date of initial examination, and pre-pregnancy weight are abstracted from medical records (also described in the protocol, Weights Abstracted from Prenatal Charts). Weight in pregnancy is measured at prenatal or research visits using a research protocol (see Measured Weight). Height can be collected by self-report (see Self-reported Height) or, preferably, by measurement in the 1st trimester (see Standing Height).

Most obstetric practices and prenatal clinics use a standardized form to chart prenatal course. The American Congress of Obstetricians and Gynecologists (ACOG, formerly the American College of Obstetricians and Gynecologists) has an Antenatal Record form that is periodically upgraded and available for its members. There are others, such as the POPRAS (Problem Oriented Perinatal Risk Assessment System) or Hollister Maternal/Newborn Record System forms, which are also in common use. All of the standardized forms have places or spaces to report information on gestational age, pre-pregnancy weight, and dates of examination, and these can be abstracted. For women carrying a singleton fetus, the expected schedule of prenatal visits suggested by ACOG is monthly through the 7th month (28 weeks), every 2-3 weeks through the 9th month (36 weeks), and weekly thereafter until delivery. The gestational age at delivery can be found in the labor and delivery chart.

An example of the relevant section of the ACOG Antenatal Record Form B (Initial Physical Exam) which charts date of exam, pre-pregnancy weight, and height:

An example of the relevant section of the ACOG Antenatal Record Form C which contains the date of the woman’s last menstrual period (LMP) and estimated due date(s) (EDD) for establishing (or correcting) gestational age at each prenatal visit:

Gestational age (written with both weeks and days, e.g., 39 weeks and 0 days or 39 + 0) is calculated using the best obstetrical EDD based on the following formula:

Gestational Age = (280 - (EDD - Reference Date))/ 7

Personnel and Training Required

For the aspects of the measures requiring chart review, the abstracter should be trained in medical terminology and records review; for measuring weights, the examiner should be trained as for Measured Weight.

Equipment Needs

Paper-and-pencil (for chart review) and/or digital scale or beam balance scale.

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Physical measurement and/or medical record abstraction

Lifestage

Pregnancy

Participants

Women who have had a pregnancy (20 weeks or longer) or are currently pregnant.

Selection Rationale

Weight and weight gain in pregnancy are associated with adverse pregnancy outcomes, including risk for low and high birth weight (i.e., small-for-gestational [SGA] and large-for-gestational age [LGA] newborns); risk for preeclampsia and gestational diabetes; and risk for cesarean delivery. Maternal weight gain below recommended is associated with a lower birth weight. Maternal weight gain in excess of recommendations is associated with a high birth weight and, especially among those women who were normal weight before pregnancy, has also been independently associated with risk of overweight and obesity in the offspring.

Language

English

Standards

Standard	Name	ID	Source
caDSR Form	PhenX PX021702 - Serial Pregnancy Weight Weights Measured During Gestat	5807337	caDSR Form

Derived Variables

Total Weight Gain in Pregnancy, Rates of Weight Gain

Process and Review

The Expert Review Panel #1 reviewed the measures in the Anthropometrics, Diabetes, Physical Activity and Physical Fitness, and Nutrition and Dietary Supplements domains.

Guidance from the ERP includes:

a. Added a new measure

b. New Data Dictionary

Protocol Name from Source

American Congress of Obstetricians and Gynecologists (ACOG), Antenatal Record Forms B and C

Source

American Congress of Obstetricians and Gynecologists (http://www.acog.org/).

General References

Institute of Medicine, Committee to Reexamine IOM Pregnancy Weight Guidelines. (2009). Weight gain during pregnancy: Reexamining the guidelines. K. M. Rasmussen & A. L. Yaktine (Eds.). Washington, DC: National Academy Press.

Rasmussen, K. M., Catalano, P. M., & Yaktine, A. L. (2009). New guidelines for weight gain during pregnancy: what obstetrician/gynecologists should know. Current Opinion in Obstetrics and Gynecology, 21, 521-526.

Protocol ID

21702

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX021702_SerialWeights_Prenatal_Date_Visit_1
	PX021702020100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_10
	PX021702110100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_2
	PX021702030100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_3
	PX021702040100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_4
	PX021702050100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_5
	PX021702060100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_6
	PX021702070100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_7
	PX021702080100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_8
	PX021702090100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_Date_Visit_9
	PX021702100100	What is the date of today's prenatal examination?	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_1
	PX021702020200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_10
	PX021702110200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_2
	PX021702030200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_3
	PX021702040200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_4
	PX021702050200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_5
	PX021702060200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_6
	PX021702070200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_7
	PX021702080200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_8
	PX021702090200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_GestationalAge_Visit_9
	PX021702100200	What is the patient's gestational age at more today's prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_1
	PX021702020300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_10
	PX021702110300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_2
	PX021702030300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_3
	PX021702040300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_4
	PX021702050300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_5
	PX021702060300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_6
	PX021702070300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_7
	PX021702080300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_8
	PX021702090300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Height_Visit_9
	PX021702100300	What is the patient's height at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_InitialExamination_Date
	PX021702010100	What is the date of initial examination	N/A
PX021702_SerialWeights_Prenatal_InitialExamination_Height
	PX021702010200	What is the patient's height measured at more initial examination? show less	Variable Mapping
PX021702_SerialWeights_Prenatal_InitialExamination_Weight
	PX021702010300	What is the patient's weight measured at more initial examination? show less	Variable Mapping
PX021702_SerialWeights_Prenatal_Weight_Visit_1
	PX021702020400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_10
	PX021702110400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_2
	PX021702030400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_3
	PX021702040400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_4
	PX021702050400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_5
	PX021702060400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_6
	PX021702070400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_7
	PX021702080400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_8
	PX021702090400	What is the patient's weight at today's more prenatal examination? show less	N/A
PX021702_SerialWeights_Prenatal_Weight_Visit_9
	PX021702100400	What is the patient's weight at today's more prenatal examination? show less	N/A

Anthropometrics

Measure Name

Serial Pregnancy Weight Gain

Release Date

October 1, 2015

Definition

Serial changes in weight of the participant during the course of pregnancy for the most recent pregnancy.

Purpose

Serial weights are used to assess patterns of weight gain over various periods, such as trimesters, and rates of weight gain, especially in the last two trimesters. Rates of weight gain are the only weight gain measures that are not dependent on a recalled or self-reported pre-pregnancy weight. Gestational weight gain and rates are generally interpreted based on a woman’s pre-pregnancy body mass index (BMI, kg/m²).

Keywords

Anthropometrics, weight, body mass index, BMI, gestation, ACOG

Measure Protocols

Protocol ID	Protocol Name
21701	Serial Pregnancy Weight - Weights Abstracted from Prenatal Charts
21702	Serial Pregnancy Weight - Weights Measured During Gestation

Publications

Chia, A. R., et al. (2020) Maternal plasma metabolic markers of neonatal adiposity and associated maternal characteristics: The GUSTO study. Scientific Reports. 2020 June; 10(1). doi: 10.1038/s41598-020-66026-5

Mapping for PX021702_SerialWeights_Prenatal_InitialExamination_Height

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Jackson Heart Study (JHS) Cohort	phv00181213	Standing height in centimeters at first participant visit
NHLBI ARIC Candidate Gene Association Resource (CARe)	phv00190310	Standing height in cm. at first participant visit
T2D-GENES: San Antonio Mexican American Family Studies (SAMAFS)	phv00171712	Height at the first study visit

Mapping for PX021702_SerialWeights_Prenatal_InitialExamination_Weight

dbGAP Study	dbGAP Variable	dbGAP Variable Description
Jackson Heart Study (JHS) Cohort	phv00181211	Weight in kilograms at first participant visit
NHLBI ARIC Candidate Gene Association Resource (CARe)	phv00190307	Weight in kg. at first participant visit
T2D-GENES: San Antonio Mexican American Family Studies (SAMAFS)	phv00171721	Weight at the first study visit