Protocol - Alcohol - 30-Day Quantity and Frequency

Description

Measurements of respondent’s 30-day quantity and frequency of consumption of alcohol.

Specific Instructions

Respondents are asked the 30-day frequency question only if they answered "yes" to the Alcohol - Lifetime Use measure. Alcohol is defined as any type of alcohol (including coolers, beer, wine, champagne) and liquor (e.g., whiskey, rum, gin, vodka, scotch, or liqueurs).

Availability

Available

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Protocol

The Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released it might be damaging to an individual’s employability, lead to social stigmatization, or other consequences.

For information on obtaining a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants, please go to the National Human Genome Research Institute’s Institutional Review Board website.

Respondents are asked the following two questions: one regarding the frequency of consumption (number of days), and a second regarding the usual quantity of consumption (number of drinks) on drinking days.

1. Think specifically about the past 30 days, from [DATEFILL*], up to and including today. During the past 30 days, on how many days did you drink one or more drinks of an alcoholic beverage?

# OF DAYS: ____ [RANGE: 0 - 30]

Don’t Know / Refused

2. On the days that you drank during the past 30 days, how many drinks did you usually have each day? Count as a drink a can or bottle of beer; a wine cooler or a glass of wine, champagne, or sherry; a shot of liquor or a mixed drink or cocktail.

# OF DRINKS: ____ [RANGE: 1 - 90]

Don’t Know / Refused

* DATEFILL is the date 30 days prior to the date of the interview.

Notes to interviewer:

Definition of a standard drink: 1 12oz bottle of beer, 1 glass 4oz non-fortified wine, 1 mixed drink with 1oz liquor.
If respondent needs a visual reference for the size of a drink, the flashcards from the Wave 1 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) study are provided below:

Personnel and Training Required

If an interviewer prepares the survey for self-administration, the interviewer must be trained and found competent to conduct personal interviews with individuals from the general population.

Equipment Needs

While the source instrument was developed for administration by computer, the PhenX Working Group acknowledges that these questions can be administered in a noncomputerized format.

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self-administered questionnaire

Lifestage

Adult

Participants

≥18 years of age

Selection Rationale

The protocol from the National Survey on Drug Use and Health was selected because this survey is a primary source of information on the 30-day use of drugs, alcohol, and tobacco in the civilian, noninstitutionalized population of the United States. The study was initiated in 1971 and is currently conducted on an annual basis.

Language

Chinese, English, Other languages available at source

Standards

Standard	Name	ID	Source
Logical Observation Identifiers Names and Codes (LOINC)	Alcohol 30D quantity frequency proto	62547-5	LOINC
Human Phenotype Ontology	Alcoholism	HP:0030955	HPO
caDSR Form	PhenX PX030301 - Alcohol 30 Day Quantity And Frequency	5807737	caDSR Form

Derived Variables

None

Process and Review

The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.

Guidance from ERP 3 includes:

• No significant changes to measure

Back-compatible: NA no changes to Data Dictionary

Previous version in Toolkit archive (link)

Protocol Name from Source

National Survey on Drug Use and Health (NSDUH), 2015 & National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Epidemiologic Survey on Alcohol and Related Conditions, Wave 1 (NESARC - WAVE 1)/Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV)

Source

2008 National Survey on Drug Use and Health. CAI Specifications for Programming, English Version; November 2007. (questions AL06 and AL07).

National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Epidemiologic Survey on Alcohol and Related Conditions. Wave 1 (NESARC - WAVE 1). Alcohol Use Disorder and Associated Disabilities Interview Schedule - Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition Version (AUDADIS-IV). Flashcard Booklet, Flashcards 13A-C, 16A-C, and 17A-C.

Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, P. S., Kay, W., & Pickering R. (2003). The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): Reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug and Alcohol Dependence, 71(1), 7-16.

General References

For information regarding alcohol consumption during the last 30 days among women who are pregnant, please refer to the Centers for Disease Control and Prevention (CDC) National Center on Birth Defects & Developmental Disabilities Fetal Alcohol Syndrome website and the CDC Behavioral Risk Factor Surveillance System website.

Protocol ID

30301

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX030301_Alcohol_30Day_Frequency
	PX030301010000	Think specifically about the past 30 days, more from [DATEFILL], up to and including today. During the past 30 days, on how many days did you drink one or more drinks of an alcoholic beverage? show less	Variable Mapping
PX030301_Alcohol_30Day_Frequency_Coded
	PX030301010100	Think specifically about the past 30 days, more from [DATEFILL], up to and including today. During the past 30 days, on how many days did you drink one or more drinks of an alcoholic beverage? show less	N/A
PX030301_Alcohol_30Day_Quantity
	PX030301020000	On the days that you drank during the past more 30 days, how many drinks did you usually have each day? Count as a drink a can or bottle of beer; a wine cooler or a glass of wine, champagne, or sherry; a shot of liquor or a mixed drink or cocktail. show less	Variable Mapping
PX030301_Alcohol_30Day_Quantity_Coded
	PX030301020100	On the days that you drank during the past more 30 days, how many drinks did you usually have each day? Count as a drink a can or bottle of beer; a wine cooler or a glass of wine, champagne, or sherry; a shot of liquor or a mixed drink or cocktail. show less	N/A

Alcohol, Tobacco and Other Substances

Measure Name

Alcohol - 30-Day Quantity and Frequency

Release Date

February 6, 2009

Definition

Questions asking the respondent about quantity and frequency of alcohol consumption during the past 30 days.

Purpose

This measure can be used to assess the participant’s recent consumption of alcohol. The potential of recall bias can be reduced by assessing the respondent’s recent use.

Keywords

alcohol, exposure, alcohol use, alcohol abuse, alcohol use, coolers, beer, wine, champagne, liquor, whiskey, rum, gin, vodka, scotch, liqueurs, sherry, cocktail, mixed drink, National Institute on Alcohol Abuse and Alcoholism, NIAAA, National Epidemiologic Survey on Alcohol and Related Conditions, NESARC, Alcohol Use Disorder and Associated Disabilities Interview Schedule, AUDADIS, Diagnostic and Statistical Manual of Mental Disorders, National Survey on Drug Use and Health, NSDUH, gerontology, aging, geriatrics

Measure Protocols

Protocol ID	Protocol Name
30301	Alcohol - 30-Day Quantity and Frequency

Publications

Sarfan, L. D., et al. (2023) The Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) for serious mental illness in community mental health part 1: study protocol for a hybrid type 2 effectiveness-implementation cluster-randomized trial. Trials. 2023 March; 24(1): 198. doi: 10.1186/s13063-023-07148-9

Barbirou, M., et al. (2020) Western influenced lifestyle and Kv2.1 association as predicted biomarkers for Tunisian colorectal cancer. BMC Cancer. 2020 November; 20: Article Number: 1086. doi: 10.1186/s12885-020-07605-7

Rose, S. W., et al. (2019) Perceived racial/ethnic discrimination, marketing, and substance use among young adults. Journal of Ethnicity in Substance Abuse. 2019 October; 18(4): 558-577. doi: 10.1080/15332640.2018.1425949

Juan, J., et al. (2017) Joint Effects of PON1 Polymorphisms and Vegetable Intake on Ischemic Stroke: A Family-Based Case Control Study. Int J Mol Sci. 2017 December; 18(12): E2652. doi: 10.3390/ijms18122652

Tarleton, E. K., et al. (2017) Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 June; 12(6): e0180067. doi: 10.1371/journal.pone.0180067

Kwok, R. K., et al. (2017) The GuLF STUDY: A Prospective Study of Persons Involved in the Deepwater Horizon Oil Spill Response and Clean-Up. Environ Health Perspect. 2017 April; 125(4): 570-578. doi: 10.1289/EHP715

Salmoirago-Blotcher, E., et al. (2017) Phone-delivered mindfulness training to promote medication adherence and reduce sexual risk behavior among persons living with HIV: Design and methods. Contemp Clin Trials. 2017 February; 53: 162-170. doi: 10.1016/j.cct.2016.12.016

McCarty, C.A., Berg, R., Rottscheit, C.M., Waudby, C.J., Kitchner, T., Brilliant, M., Ritchie, M.D. (2014) Validation of PhenX measures in the personalized medicine research project for use in gene/environment studies. BMC Med Genomics. 2014 January; 7: 3. doi: 10.1186/1755-8794-7-3

Mapping for PX030301_Alcohol_30Day_Frequency

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GenADA/LONG/Imaging (Genetic Alzheimer's Disease Associations)	phv00081806	Last 30 days: How many days did you have at least one alcohol drink?
Genetic Multiple Sclerosis Associations - GeneMSA	phv00072936	During the past 30 days, on how many days did you have at least one alcohol drink?
NEIGHBOR Consortium Glaucoma GWAS	phv00129665	# of days drinking in past month (0 to 30), 999: Missing
The Vaginal Microbiome: Disease, Genetics and the Environment	phv00090478	How many ocassions have you had alcohol in the last 30 days?
The Vaginal Microbiome: Disease, Genetics and the Environment	phv00090481	On how many occasions have you had four or more alcoholic drinks in one sitting in the last 30 days?

Mapping for PX030301_Alcohol_30Day_Quantity

dbGAP Study	dbGAP Variable	dbGAP Variable Description
GenADA/LONG/Imaging (Genetic Alzheimer's Disease Associations)	phv00081803	Amount of alcohol per day in last 30 days
GWAS on Cataract and HDL in the PMRP	phv00181345	On the days that you drank during the past 30 days, how many drinks did you usually have each day? Count as a drink a can or bottle of beer; a wine cooler or a glass of wine, champagne, or sherry; a shot of liquor or a mixed drink or cocktail.
NEIGHBOR Consortium Glaucoma GWAS	phv00129666	# of drinks in past month (0-90 max), 999: Missing
NHLBI Cleveland Family Study (CFS) Candidate Gene Association Resource (CARe)	phv00122304	Average consumption of alcohol past month (A)