Protocol - Medications (Current and Past Use of Pain Relievers, Statins, and Steroids)

Personnel and Training Required

None

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self-administered questionnaire

Lifestage

Adult

Participants

Female, current and former public school teachers or administrators who participate in the California State Teachers Retirement System (STRS)*

*While this protocol was used in a study of women, the Cancer Working Group deems it appropriate to use with adult males.

Selection Rationale

This protocol was selected because it obtains information about current and past prescription and over-the-counter (OTC) medication use potentially related to cancer risk.

Language

English

Standards

Standard	Name	ID	Source
Logical Observation Identifiers Names and Codes (LOINC)	Meds pain statins steroids proto	62732-3	LOINC
caDSR Form	PhenX PX071201 - Medications (Current and Past Use of Pain Relievers, Statins, and Steroids)	5963003	caDSR Form

Derived Variables

None

Process and Review

Not applicable.

Protocol Name from Source

The California Teachers Study, Follow-Up Survey 4, 2005-2006

Source

State of California, The California Teachers Study, Follow-Up Survey 4, 2005–2006, questions 5–7, page 3.

General References

Protocol ID

71201

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX071201_Acetaminophen_Regular
	PX071201010601	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? Acetaminophen (Aspirin-free Excedrin, Tylenol, Tempra). show less	N/A
PX071201_Acetaminophen_Stop
	PX071201020601	Did you stop the regular use of any of the more following medications during the past 3 years? Acetaminophen. show less	N/A
PX071201_Acetaminophen_Stop_Reason
	PX071201020602	Why did you stop regular use? Acetaminophen.	N/A
PX071201_Acetaminophen_Tablets_Quantity
	PX071201010602	Total tablets per week? Acetaminophen more (Aspirin-free Excedrin, Tylenol, Tempra). show less	N/A
PX071201_Aspirin_Regular
	PX071201010201	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? Aspirin or aspirin-containing product (Bayer, Bufferin, Excedrin). show less	N/A
PX071201_Aspirin_Stop
	PX071201020201	Did you stop the regular use of any of the more following medications during the past 3 years? Aspirin or aspirin-containing product. show less	N/A
PX071201_Aspirin_Stop_Reason
	PX071201020202	Why did you stop regular use? Aspirin or more aspirin-containing product. show less	N/A
PX071201_Aspirin_Tablets_Quantity
	PX071201010202	Total tablets per week? Aspirin or more aspirin-containing product (Bayer, Bufferin, Excedrin). show less	N/A
PX071201_Baby_Low_Aspirin_Regular
	PX071201010101	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? 'Baby' or low-dose aspirin. show less	N/A
PX071201_Baby_Low_Aspirin_Stop
	PX071201020101	Did you stop the regular use of any of the more following medications during the past 3 years? 'Baby' or low-dose aspirin. show less	N/A
PX071201_Baby_Low_Aspirin_Stop_Reason
	PX071201020102	Why did you stop regular use? 'Baby' or more low-dose aspirin. show less	N/A
PX071201_Baby_Low_Aspirin_Tablets_Quantity
	PX071201010102	Total tablets per week? 'Baby' or low-dose more aspirin. show less	N/A
PX071201_Cox2_Inhibitor_Regular
	PX071201010501	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? Cox-2 inhibitor (Celebrex, Vioxx). show less	N/A
PX071201_Cox2_Inhibitor_Stop
	PX071201020501	Did you stop the regular use of any of the more following medications during the past 3 years? Cox-2 inhibitor. show less	N/A
PX071201_Cox2_Inhibitor_Stop_Reason
	PX071201020502	Why did you stop regular use? Cox-2 inhibitor.	N/A
PX071201_Cox2_Inhibitor_Tablets_Quantity
	PX071201010502	Total tablets per week? Cox-2 inhibitor more (Celebrex, Vioxx). show less	N/A
PX071201_Ibuprofen_Regular
	PX071201010301	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? Ibuprofen (Advil, Motrin). show less	N/A
PX071201_Ibuprofen_Stop
	PX071201020301	Did you stop the regular use of any of the more following medications during the past 3 years? Ibuprofen. show less	N/A
PX071201_Ibuprofen_Stop_Reason
	PX071201020302	Why did you stop regular use? Ibuprofen.	N/A
PX071201_Ibuprofen_Tablets_Quantity
	PX071201010302	Total tablets per week? Ibuprofen (Advil, Motrin).	N/A
PX071201_Naproxen_Ketoprofen_Regular
	PX071201010401	Do you currently take any of the following more pain-relieving medications regularly (at least once a week)? Naproxen, ketoprofen or other non-steroidal (Aleve, Feldene, Indocin, Naprosyn, Orudis, Relafen). show less	N/A
PX071201_Naproxen_Ketoprofen_Stop
	PX071201020401	Did you stop the regular use of any of the more following medications during the past 3 years? Naproxen, ketoprofen or other non-steroidal. show less	N/A
PX071201_Naproxen_Ketoprofen_Stop_Reason
	PX071201020402	Why did you stop regular use? Naproxen, more ketoprofen or other non-steroidal. show less	N/A
PX071201_Naproxen_Ketoprofen_Tablets_Quantity
	PX071201010402	Total tablets per week? Naproxen, ketoprofen more or other non-steroidal (Aleve, Feldene, Indocin, Naprosyn, Orudis, Relafen). show less	N/A
PX071201_Statin
	PX071201030100	In the past 3 years, please indicate if you more have taken either of the following types of medications. Statin medications such as lovastatin (Mevacor), atorvastatin (Lipitor), rosuvastain (Crestor), pravastatin (Pravachol), simvastatin (Zocor), fluvast show less	N/A
PX071201_Steroid_Pill
	PX071201030200	In the past 3 years, please indicate if you more have taken either of the following types of medications. Steroid medication in pill form such as prednisone, dexamethasone (Decadron), solumedrol (Medrol dose-pack) show less	N/A

Cancer

Measure Name

Medications (Current and Past Use of Pain Relievers, Statins, and Steroids)

Release Date

December 30, 2009

Definition

Measure to assess current and past use of prescription and over-the-counter (OTC) pain-relieving medications, statins, steroids, anti-inflammatory medications, and inhaled bronchodilators

Purpose

Taking certain prescription and over-the-counter (OTC) medication may modify cancer risk. Assessing current and past use of prescription and OTC medications will help quantify either increased or decreased risk associated with these medications.

Keywords

cancer, prescription, Drugs, OTC, over-the-counter, statins, steroids, aspirin, Ibuprofen, Cox 2 inhibitor, Acetaminophen, anti-inflammatory, medication, medicine, The California Teachers Study (CTS)

Measure Protocols

Protocol ID	Protocol Name
71201	Medications (Current and Past Use of Pain Relievers, Statins, and Steroids)

Publications

Kwok, R. K., et al. (2017) The GuLF STUDY: A Prospective Study of Persons Involved in the Deepwater Horizon Oil Spill Response and Clean-Up. Environ Health Perspect. 2017 April; 125(4): 570-578. doi: 10.1289/EHP715