Protocol - Lung Function - Lung Volume
- Arterial Blood Gas (ABG)
- Bronchodilator Responsiveness (BDR)
- Chest Computed Tomography (CT)
- Chest X-ray
- Exercise Capacity/Six-Minute Walk Test
- Lung Function - Diffusion Capacity
- Peak Expiratory Flow Rate (PEFR)
- Personal and Family History of Respiratory Symptoms/Diseases - Adult
- Personal and Family History of Respiratory Symptoms/Diseases - Child
- Pulse Oximetry (Exercise)
- Pulse Oximetry (Rest)
- Quality of Life as Affected by Respiratory Disease
- Respiratory Rate - Adult
- Respiratory Rate - Child
- Respiratory Rate - Infant
- Sleep Apnea - Adult
- Sleep Apnea - Child
- Spirometry - Adult
- Spirometry - Child
Description
The American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the measurement of lung volume testing outline how to obtain measurement of functional residual capacity (FRC) using body plethysmography, nitrogen washout, helium dilution, and imaging techniques. In addition, this source contains details regarding the assessment of total lung capacity (TLC), vital capacity (VC), reserve volume (RV), expiratory reserve volume (ERV), and inspiratory capacity (IC).
These recommendations for standardization of the measurement of lung volume testing are part of a series of recommendations by the ATS/ERS Task Force for the standardization of lung function testing, which can be found on the ATS website at www.thoracic.org/statements/pulmonary-function.php. Detailed information regarding patient preparation is included in the general considerations document for lung function testing in this series.
Specific Instructions
A comprehensive evaluation of lung function requires investigation of various aspects of the lung, such as lung volumes and diffusion capacity. Hence, the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force have published a series of documents regarding pulmonary function testing. The Sickle Cell Disease: Cardiovascular, Pulmonary, and Renal Working Group recommends researchers access the ATS website (www.thoracic.org/) to view other documents in this series that may apply to their area of research.
Additionally, although there are various methods to measure functional residual capacity (FRC), the Working Group views body plethysmography as the most accurate, particularly when airflow obstruction is a possible underlying condition.
Availability
Protocol
Personnel and Training Required
Certified respiratory therapist
Equipment Needs
Equipment needed for the calculation of lung volumes are outlined in the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force recommendations for standardisation of the measurement of lung volumes can be found here as well as on the ATS website here.
Requirements
Requirement Category | Required |
---|---|
Major equipment | Yes |
Specialized training | Yes |
Specialized requirements for biospecimen collection | No |
Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Clinical assessment
Lifestage
Child, Adolescent, Adult, Senior, Pregnancy
Participants
Individuals age 8 years old and older.
Selection Rationale
The Sickle Cell Disease Cardiovascular, Pulmonary, and Renal Working Group recommends the American Thoracic Society (ATS) and the European Respiratory Society (ERS) Task Force 2005 recommendations for standardisation of the measurement of lung volumes because this document integrates and consolidates the task force recommendations and the recommendations from various National Heart, Lung, and Blood Institute (NHLBI) workshops.
Language
English
Standards
Standard | Name | ID | Source |
---|---|---|---|
Human Phenotype Ontology | Restrictive ventilatory defect | HP:0002091 | HPO |
caDSR Form | PhenX PX810401 - Lung Function Lung Volume | 6252184 | caDSR Form |
Derived Variables
None
Process and Review
Not applicable.
Protocol Name from Source
Wanger, J. et al. Standardization of the measurement of lung volumes. EUR RESPIR J, 2005
Source
Wanger, J., Clausen, J. L., Coates, A., Pedersen, O. F., Brusasco, V., Burgos, F., Casaburi, R., Crapo, R., Enright, P., van der Grinten, C. P. M., Gustafsson, P., Hankinson, J., Jensen, R., Johnson, D., MacIntyre, N., McKay, R., Miller, M. R., Navajas, D., Pellegrino, R., & Viegi, G. (2005). Standardisation of the measurement of lung volumes. European Respiratory Journal, 26, 511-522. doi: 10.1183/09031936.05.00035005
General References
Arteta, M., Campbell, A., Nouraie, M., Rana, S., Onyekwere, O. C., Ensing, G., Sable, C., Dham, N., Darbari, D., Luchtman-Jones, L., Kato, G. J., Gladwin, M. T., Castro, O. L., Minniti, C. P., & Gordeuk, V. R. (2014). Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia. Journal of Pediatric Hematology/Oncology, 36(3), 185-189.
Lunt, A., Desai, S. R., Wells, A. U., Hansell, D. M., Mushemi, S., Melikian, N., Shah, A. M., Thein, S. L., & Greenough, A. (2014). Pulmonary function, CT and echocardiographic abnormalities in sickle cell disease, Thorax 69(8), 746-751.
Protocol ID
810401
Variables
Export VariablesVariable Name | Variable ID | Variable Description | dbGaP Mapping | |
---|---|---|---|---|
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Calibration | ||||
PX810401390105 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Calibration_Controls | ||||
PX810401390106 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantPressure | ||||
PX810401390301 | If volume-displacement plethysmograph, what more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantPressure_Airflow | ||||
PX810401390101 | If flow plethysmograph, what is the airflow more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_ConstantVolume | ||||
PX810401390201 | If variable-pressure plethysmograph, what is more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Frc | ||||
PX810401390104 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Measurement_Technique | ||||
PX810401390103 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Transducer | ||||
PX810401390102 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_BodyPleth_Type | ||||
PX810401390000 | If body plethysmography method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Current_BarometricPressure | ||||
PX810401150000 | What is the current barometric pressure? | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Current_Temperature | ||||
PX810401140000 | What is the current ambient temperature? | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Current_Time | ||||
PX810401160000 | What is the current time? | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Equipment_Closed_Circuit | ||||
PX810401230000 | Since the previous subject, if a more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Equipment_OpenCircuit_Mouthpiece | ||||
PX810401250000 | Since the previous subject, if an more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Equipment_OpenCircuit_Replacement | ||||
PX810401240000 | Since the previous subject, if an more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Equipment_Reusable_Components | ||||
PX810401220000 | Has reusable equipment (such as mouthpieces, more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Erv | ||||
PX810401370202 | If first method, what is the reported value more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Frc | ||||
PX810401370201 | If first method, what is the reported value more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_FirstMethod_Ivc | ||||
PX810401370203 | If first method, what is the reported value more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Flow | ||||
PX810401410900 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Range | ||||
PX810401410600 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Stability | ||||
PX810401410700 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_Type | ||||
PX810401410400 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Analyzer_TypeOther | ||||
PX810401410500 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_CalibrationStep | ||||
PX810401410200 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Calibration_Control | ||||
PX810401411800 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_CarbonDioxide | ||||
PX810401411000 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_DeadSpace | ||||
PX810401411300 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Flow | ||||
PX810401410300 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Leak_Check | ||||
PX810401411600 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Measurement_Technique | ||||
PX810401411400 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Oxygen_Recalibration | ||||
PX810401410800 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Quality_Control | ||||
PX810401411500 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Spirometer_QualityControl | ||||
PX810401410100 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Stability_Temperature | ||||
PX810401411700 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Temperature | ||||
PX810401411100 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Helium_Temperature_Sensor | ||||
PX810401411200 | If helium dilution method is used to measure more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Imaging_Technique | ||||
PX810401420200 | If the subject has limited ability to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Imaging_Technique_Other | ||||
PX810401420300 | If the subject has limited ability to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Inline_Filtered | ||||
PX810401280000 | If in-line filters are being used, does the more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_MethodOf_Measurement | ||||
PX810401370100 | Which method from lung volume measurement is more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Method_Frc | ||||
PX810401380000 | Which method is used for measuring forced more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Myocardial_Infarction | ||||
PX810401020000 | Has the subject suffered from myocardial more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_BreathingValve | ||||
PX810401400400 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration | ||||
PX810401400200 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Controls | ||||
PX810401400900 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Day | ||||
PX810401400800 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Calibration_Zero | ||||
PX810401400600 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Measurement_Technique | ||||
PX810401400500 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Quality_Control | ||||
PX810401400100 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_Recalibration | ||||
PX810401400700 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Nitrogen_SamplingRate | ||||
PX810401400300 | If nitrogen washout method is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Competency | ||||
PX810401310000 | For personnel directly involved in pulmonary more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_CompetencyExam | ||||
PX810401330000 | Has personnel passed a written and practical more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_FormalTraining | ||||
PX810401300000 | For personnel directly involved in pulmonary more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_NotebookOf_Records | ||||
PX810401350000 | Are personnel maintaining a notebook of more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Notebook_Detail | ||||
PX810401360000 | Are there detailed statements and/or more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_Qualifications | ||||
PX810401290000 | Do personnel have the sufficient education more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_RefreshTraining | ||||
PX810401340000 | If it has been more than 3 years since more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Personnel_TrainingProgram | ||||
PX810401320000 | Has personnel completed training similar to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Ic | ||||
PX810401370306 | If second method, and using the slow EVC more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Ivc | ||||
PX810401370304 | If second method, and using the IVC/ERV more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Tlc | ||||
PX810401370307 | If second method, what is the calculated more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Vc | ||||
PX810401370303 | If second method, which approach is used to more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Approach_Vc | ||||
PX810401370305 | If second method, and using the IVC/ERV more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Erv | ||||
PX810401370302 | If second method, what is the reported value more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_SecondMethod_Frc | ||||
PX810401370301 | If second method, what is the reported value more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Spirometer_Recalibration | ||||
PX810401260000 | If the spirometer was disassembled and more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subjects_Infected_Precautions | ||||
PX810401270000 | For subjects with transmissible infectious more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_AbilityTo_Cooperate | ||||
PX810401200000 | Does the subject show signs of limited more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Activities | ||||
PX810401040000 | Was the subject involved in any of the more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Age | ||||
PX810401060000 | What is the subject's age? | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Arm_Span | ||||
PX810401080200 | If so, what is the subject's arm span from more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Bmi | ||||
PX810401110000 | What is the subject's body mass index? | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Conditions | ||||
PX810401030000 | Does the subject suffer from any of the more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Denture | ||||
PX810401130000 | Does the subject wear any denture or dental more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_DiseaseOr_Illness | ||||
PX810401190000 | Does the subject currently suffer from upper more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Height | ||||
PX810401070000 | What is the subject's height? (without more | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Knee_Height | ||||
PX810401090200 | If so, what is the subject's knee height? | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications | ||||
PX810401120100 | Is the subject currently taking any more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications_LastTime | ||||
PX810401120300 | If so, when was the last time the drugs were more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Medications_Type | ||||
PX810401120200 | If so, what type of medication is the more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_OralSores | ||||
PX810401210000 | Does the subject suffer from open oral sores more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_OtherHandicap | ||||
PX810401090100 | Does the subject suffer from any handicap more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Position | ||||
PX810401050100 | Which position will the subject be in for more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Position_Other | ||||
PX810401050200 | Which position will the subject be in for more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_EquipmentTester | ||||
PX810401170200 | If so, is the equipment and operator from more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_OrderConserved | ||||
PX810401180000 | Is the planned order of lung function tests more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Repeat_TimeRestriction | ||||
PX810401170300 | If so, is the current test time within 2 more | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Return_Testing | ||||
PX810401170100 | Is the subject returning for repeat testing? | N/A | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Thoracic_Deformity | ||||
PX810401080100 | Does the subject suffer from any deformity more | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_Subject_Weight | ||||
PX810401100000 | What is the subject's weight? | Variable Mapping | ||
PX810401_Standardisation_LungVolumeMeasurement_VC | ||||
PX810401010000 | Which of the following ways is the more | N/A |
Measure Name
Lung Function - Lung Volume
Release Date
July 30, 2015
Definition
Clinical assessment to determine the volume of gas within an individual’s lung.
Purpose
This measure can be used to differentiate obstructive and restrictive pulmonary conditions and to detect and quantify symptoms associated with conditions that impact the lung, such as sickle cell disease, cystic fibrosis, and obstructive airway disease.
Keywords
Lung function, lung volume, lung physiology, diffusion capacity, DLCO, functional residual capacity, FRC, sickle cell disease, SCD, emphysema, Cystic fibrosis, CF, asbestosis, lupus, arthritis, smoking, sarcoidosis, carbon monoxide, obstructive airway disease, Pulmonary, asthma, sleep apnea, breathing, "Cardiovascular, Pulmonary, and Renal"
Measure Protocols
Protocol ID | Protocol Name |
---|---|
810401 | Lung Function - Lung Volume |
Publications
There are no publications listed for this protocol.