Protocol - Thrombosis - Catheter-related
Description
This protocol from the Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS) study captures age of participant and date of occurrence of catheter-related deep venous thrombosis or pulmonary embolism. The diagnostic method for this is also prompted.
Specific Instructions
The Sickle Cell Disease Pregnancy Working Group recommends that investigators also consider these related protocols: Thromboprophylaxis and Thrombosis - Venous, non-catheter-related. They also suggest that investigators capture the start and stop dates of anticoagulation as well as the trimester. If possible, determine the timing of thrombosis relative to line placement.
Availability
Protocol
Thrombosis – Catheter-related
Age at event (Catheter-related thrombosis): ______________
CATHETER RELATED THROMBOSIS:
Year: ________________
Site: _________________
Diagnostic method:
[ ] Doppler ultrasound
[ ] V/Q perfusion scan
[ ] CT pulmonary angiogram
Personnel and Training Required
Personnel should be trained in medical record abstraction.
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Medical record abstraction
Lifestage
Child, Adolescent, Adult, Pregnancy
Participants
Children and adults with sickle cell disease.
Selection Rationale
These questions from the Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS) study have been used in participants with sickle cell disease and may be collected from the participant or abstracted from the medical record.
Language
English
Standards
| Standard | Name | ID | Source |
|---|
Derived Variables
None
Process and Review
Not Applicable
Protocol Name from Source
Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS)
Source
Forté, S., De Luna, G., Abdulrehman, J., Fadiga, N., Pestrin, O., Pham Hung D'Alexandry d'Orengiani, A. L., Aneke, J. C., Guillet, H., Budhram, D., Habibi, A., Ward, R., Bartolucci, P., & Kuo, K. H. M. (2022). Thromboprophylaxis Reduced Venous Thromboembolism in Sickle Cell Patients with Central Venous Access Devices: A Retrospective Cohort Study. Journal of clinical medicine, 11(5), 1193. https://doi.org/10.3390/jcm11051193
General References
Seaman, C. D., Yabes, J., Li, J., Moore, C. G., & Ragni, M. V. (2014). Venous thromboembolism in pregnant women with sickle cell disease: a retrospective database analysis. Thrombosis research, 134(6), 1249-1252. https://doi.org/10.1016/j.thromres.2014.09.037
Protocol ID
890201
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX890201_Thrombosis_Catheter_Related_Age | ||||
| PX890201010000 | Age at event (Catheter-related thrombosis): more | N/A | ||
| PX890201_Thrombosis_Catheter_Related_Method | ||||
| PX890201040000 | Diagnostic method: | N/A | ||
| PX890201_Thrombosis_Catheter_Related_Site | ||||
| PX890201030000 | Site: _________________ | N/A | ||
| PX890201_Thrombosis_Catheter_Related_Year | ||||
| PX890201020000 | Year: ________________ | N/A | ||
Measure Name
Thrombosis
Release Date
August 5, 2024
Definition
Thrombosis is a blockage within a vessel (artery or vein), caused by a blood clot.
Purpose
Participants with certain inherited and acquired blood disorders, including sickle cell disease, have an overall increased risk of developing thrombosis. Additionally, certain acquired factors, such as pregnancy and central line placement, also increase the risk of thrombosis.
Keywords
Thrombosis, blood clot, deep vein thrombosis (DVT), pulmonary embolism, venous thromboembolism (PE)
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 890201 | Thrombosis - Catheter-related |
| 890202 | Thrombosis - Venous - non-catheter-related |
Publications
There are no publications listed for this protocol.