Protocol - Family History - Psychosis

Description

The Family Interview for Genetic Studies (FIGS) is a tool used by a trained interviewer to collect information about biological relatives of the subject who has a mental disorder. The interview is conducted with the relatives themselves and not through the subject. There are three parts to the FIGS. The General Screening Questions gather general information about all known relatives. The Face Sheet is completed for each of the first-degree relatives and any affected relatives. This abbreviated version of the FIGS includes only a Symptom Checklist for psychosis.

Specific Instructions

For a more detailed interview guide, one that includes symptom checklists for all mental disorders, the Early Psychosis Working Group recommends using the FIGS-Full Version (Family History - Multiple Mental Disorders protocol). A baseline assessment of this measure is an interview of a parent and the ill person. The optimal approach is to directly interview all available biological family members, at least out to second-degree relatives. It is important to gather this information from relatives because it can be difficult to rely on information obtained directly from the ill person. If not all relatives can be directly interviewed, one relative may be interviewed about all others.

Availability

Available

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Protocol

GO FIGS Pedigree Drawing Instructions

v. 3.21.12

Begin with the FIGS General Screening Questions (p. 1), Step 1:

Let’s go over your family tree.

Have the pedigree form ready. Place in front of participant, and once constructed, keep it in front of participant throughout interview.

Pedigree Drawing.

1. In the middle of the page, draw a symbol for the participant (circle for female, square for males). This is you. (Write participant’s name under the symbol.)

2. If participant:

a. Is only child: You told me that you have no brothers and sisters, is that correct? (If yes, above the participant’s symbol, draw a square for dad on the left, a circle for mom on the right, connect with line, and draw another line directly down to participant’s symbol. Proceed with instruction #3 below.)

b. Has siblings. You told me that you had (insert number) siblings: (insert number) brothers and (insert number) sisters. Is that correct? (If yes, proceed; if not, correct.) Do they all have the same mother and father as you?

i. YES (same biological parents): Determine where in birth order participant falls (First, second, third and so on). Above the participant’s symbol, draw a square for dad on the left, a circle for mom on the right, connect with line, and draw another line downward. From left to right, add symbols for the other full siblings from oldest (firstborn) to youngest around the proband. Write each sibling’s name underneath his/her symbol.

ii. NO: "For this family tree, I am going to ask you only about full biological siblings: your brothers/sisters who have the same mom AND dad as you." For FULL sibs only, determine where in birth order participant falls (First, second, third and so on). From left to right, add symbols for the other full siblings from oldest (firstborn) to youngest around the proband. Write each sibling’s name underneath his/her symbol.

3. Do you have any children?

a. YES: Draw a horizontal line from the participant to a partner, and drop down a line (or set of lines) to depict children. Write each child’s name underneath his/her symbol. Go to FIGS screener.

b. NO: Go to FIGS screener.

Probandʼs Initials:	_______________________________________
ID:	_______________________________________
FAMID:	_______________________________________
Age:	_______________________________________
Assessor:	_______________________________________
Date:	_______________________________________
Start time:	_______________________________________
End time:	_______________________________________

v. 11/19/09

FIGS: Proband Pedigree

FIGS: GENERAL SCREENING QUESTIONS

Interview date:				-			-
	Month				Day			Year

Family last name:

Family ID number:

Informant name:	____________________	____________________	____________________
	First	MI	Last

Informant ID:

INTERVIEWER: Before you begin, you need to generate or obtain a pedigree on which to record all of the responses to the following General Screening Questions. (See FIGS Manual for details.)

Step 1:	Let’s go over your family tree. (Include first-degree relatives only: offspring, parents, siblings.)
Step 2:	Now I am asking you to keep in mind all those in your family tree as I go through this list of questions. (Note all positive responses on the pedigree.)
	[ ] Was anyone adopted?
	[ ] Was anyone mentally retarded?
	Did anyone:
	[ ] Have problems with their nerves or emotions? Take medicine or see a doctor for it? Take lithium?
	[ ] Feel very low for a couple of weeks or more, or have a diagnosis of depression?
	[ ] Attempt or complete suicide?
	[ ] Seem overexcited (or manic) day and night, or have a diagnosis of mania?
	[ ] **Have visions, hear voices, or have beliefs that seem strange or unreal?
	[ ] **Have unusual or bizarre behavior, or have a diagnosis of schizophrenia?
	[ ] Have trouble with the police, with completing school, or with keeping a job?
	[ ] Have alcohol or drug use that caused problems (with health, family, job, or police)? Go to AA or NA, or have treatment for this?
	[ ] (Was anyone) hospitalized for psychiatric problems, or for drug or alcohol problems?
	[ ] Have inherited medical diseases such as Huntington’s disease or seizure disorder or any other disorders of the brain or nervous system?
	[ ] **(Did anyone) have few friends, or seem to be a loner?
	[ ] **(Did anyone) seem odd or eccentric in behavior or appearance?
	[ ] **(Was anyone) extremely jealous, or suspicious, or believe in magic, or see special meanings in things that no one else saw?
Step 3:	Complete a Face Sheet for each of the informant’s first-degree relatives.

FIGS: FACE SHEET

Interview date:				-			-
	Month				Day			Year

Family last name:

Family ID number:

Informant name:	____________________	____________________	____________________
	First	MI	Last

Informant ID:

Person being described name:	____________________	____________________	____________________
	First	MI	Last

Person being described ID:

Relationship to informant:

____________________________________________________________

Birthdate of person described, if known:				-			-
	Month				Day			Year

Is person described living?

0[ ]No

1[ ]Yes

9[ ]Unknown

Age and Year when last seen or known about, or died:			in
	Age			year

If deceased, cause of death::

____________________________________________________________

Suicide?

0[ ]No

1[ ]Yes

9[ ]Unknown

INTERVIEWER: Refer to General Screening Questions if necessary.

1. Write narrative:

If any General Screening Questions endorsed about this relative, code 1 and transcribe details here. Complete psychosis checklist if any *starred* items endorsed.

FIGS: PSYCHOSIS CHECKLIST

Interview date:				-			-
	Month				Day			Year

Family last name:

Family ID number:

Informant name:	____________________	____________________	____________________
	First	MI	Last

Informant ID:

Person being described name:	____________________	____________________	____________________
	First	MI	Last

PSYCHOSIS

Code for a single episode (best recalled, worst episode if possible).

1. What were his/her unusual beliefs or experiences?

Specify: ____________________________________________________________________________

	Did he/she ever…	No	Yes	Unk
1.a)	…believe people were following him/her, or that someone was trying to hurt or poison him/her?	0	1	9
1.b)	…believe someone was reading his/her mind?	0	1	9
1.c)	…believe he/she was under the control of some outside person or power or force?	0	1	9
1.d)	…believe his/her thoughts were broadcast, or that an outside force took away his/her thoughts or put thoughts into his/her head?	0	1	9
1.e)	…have any other strange or unusual beliefs?	0	1	9

If yes: Describe: _______________________________________________________________________

1.f)	…see things that were not really there?	0	1	9
1.g)	…hear voices or other sounds that were not real?	0	1	9

If yes: Describe: _______________________________________________________________________

If 1.g = 0, then skip to question 1.h

1.g.1)	(Code YES if: voice with content having no relation to depression or elation, or voice keeping up running commentary on subject’s behavior or thoughts, or two or more voices conversing.)	0	1	9
1.h)	…speak in a way that was difficult to make sense of?	0	1	9

If yes: Describe: _______________________________________________________________________

1.i)	…seem to be physically stuck in one position, or move around excitedly without purpose?	0	1	9
1.j)	…appear to have no emotions, or inappropriate emotions?	0	1	9

2. How long did the longest of these experiences last?
	Weeks

INTERVIEWER: If less than 1 week (unless successfully treated), STOP HERE. Otherwise continue, if informant is knowledgeable about this person.

Code Response

Code and describe professional treatment (Code and describe all that apply):

0[ ]None

1[ ]Inpatient: ___________________________________________________

2[ ]Outpatient: __________________________________________________

3[ ]ECT: _____________________________________________________

4[ ]Medication: __________________________________________________

9[ ]Unknown

Describe details and/or other treatment:

					Age
7.	Age of onset:

		Episodes
8.	Number of episodes (Code 001 if chronic symptoms and/or treatment since onset):
		Weeks	Years

Total illness duration (all episodes, includes active and prodromal and/or residual symptoms and/or treatment):

Code Response

10. Rate and code impairment or incapacitation:

0[ ]None

1[ ]Impaired

2[ ]Incapacitated

9[ ]Unknown

11. Interviewer judgment on reliability of this information:

1[ ]Good

2[ ]Fair

3[ ]Poor

FIGS: PSYCHOSIS CHECKLIST

Interview date:				-			-
	Month				Day			Year

Family last name:

Family ID number:

Informant name:	____________________	____________________	____________________
	First	MI	Last

Informant ID:

Person being described name:	____________________	____________________	____________________
	First	MI	Last

Person being described ID:

PSYCHOSIS

Code for a single episode (best recalled, worst episode if possible).

1. What were his/her unusual beliefs or experiences?

Specify: ________________________________________________________________________________________________________________________

Did he/she ever…

1.a) …believe people were following him/her, or that someone was trying to hurt or poison him/her?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.b) …believe someone was reading his/her mind?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.c) …believe he/she was under the control of some outside person or power or force?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.d) …believe his/her thoughts were broadcast, or that an outside force took away his/her thoughts or put thoughts into his/her head?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.e) …have any other strange or unusual beliefs?

0[ ]No

1[ ]Yes

9[ ]Unknown

If yes: Describe: ________________________________________________________________________________________________________________

1.f) …see things that were not really there?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.g) …hear voices or other sounds that were not real?

0[ ]No

1[ ]Yes

9[ ]Unknown

If yes: Describe: ________________________________________________________________________________________________________________

If no: Skip to Question 1.h.

1.g.1) (Code YES if: Voice with content having no relation to depression or elation, or voice keeping up running commentary on subject’s behavior or thoughts, or two or more voices conversing.)

0[ ]No

1[ ]Yes

9[ ]Unknown

1.h) …speak in a way that was difficult to make sense of?

0[ ]No

1[ ]Yes

9[ ]Unknown

If yes: Describe: ________________________________________________________________________________________________________________

1.i) …seem to be physically stuck in one position, or move around excitedly without any purpose?

0[ ]No

1[ ]Yes

9[ ]Unknown

1.j) …appear to have no emotions, or inappropriate emotions?

0[ ]No

1[ ]Yes

9[ ]Unknown

2. How long did the longest of these experiences last?
	Weeks

INTERVIEWER: If less than one week, unless successfully treated, STOP HERE. Otherwise continue, if informant is knowledgeable about this person.

3. Code and describe professional treatment (Code and describe all that apply):

0[ ]None

1[ ]Inpatient: ___________________________________________________

2[ ]Outpatient: __________________________________________________

3[ ]ECT: _____________________________________________________

4[ ]Medication: __________________________________________________

9[ ]Unknown

Describe details and/or other treatment: ___________________________________________________________________________________________

4.) Age of onset:

Age

5. Number of episodes (Code 001 if chronic symptoms and/or treatment since onset):
	Episodes

6. Total illness duration (all episodes, includes active and prodromal and/or residual symptoms and/or treatment).			OR
	Weeks			Years

7. Rate and code impairment or incapacitation:

0[ ]None

1[ ]Impaired

2[ ]Incapacitated

9[ ]Unknown

8. Interviewer judgement on reliability of this information:

1[ ]Good

2[ ]Fair

3[ ]Poor

Personnel and Training Required

The interviewer must be trained to conduct personal psychiatric interviews with individuals from the general population. The interviewer must be trained and found to be competent (i.e., tested by an expert) at the completion of personal interviews. The interviewer should be trained to prompt respondents further if a "don’t know" response is provided.

Equipment Needs

The PhenX Working Group acknowledges these questions can be administered in a computerized or noncomputerized format (i.e., paper-and-pencil instrument). Computer software is necessary to develop computer-assisted instruments. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	Yes

Mode of Administration

Interviewer-administered questionnaire

Lifestage

Adult

Participants

Adults, ages 18 years and older

Selection Rationale

The use of the Family Interview for Genetic Studies (FIGS) has made it possible to advance in the performance of family studies for research in genetic psychiatry. The questionnaire is reliable and valid for gathering diagnostic information about relatives of a subject.

Language

English

Standards

Standard	Name	ID	Source
Human Phenotype Ontology	Psychosis	HP:0000709	HPO
caDSR Form	PhenX PX660702 - Family History Psychosis	6916807	caDSR Form

Derived Variables

None

Process and Review

Not applicable.

Protocol Name from Source

Family Interview for Genetic Studies (FIGS) - Abbreviated Version

Source

Calkins, M. E., Merikangas, K. R., Moore, T. M., Burstein, M., Behr, M. A., Satterthwaite, T. D., Ruparel, K., Wolf, D. H., Roalf, D. R., Mentch, F. D., Qiu, H., Chiavacci, R., Connolly, J. J., Sleiman, P. M., Gur, R. C., Hakonarson, H., & Gur, R. E. (2015). The Philadelphia Neurodevelopmental Cohort: Constructing a deep phenotyping collaborative. Journal of Child Psychology and Psychiatry, 56(12), 1356-1369.

General References

Maxwell, M. E. (1992). Family Interview for Genetic Studies (FIGS): Manual For FIGS. Bethesda, MD: Clinical Neurogenetics Branch, Intramural Research Program, National Institute of Mental Health.

Protocol ID

660702

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX660702_FamilyHistory_Psychosis_Figs_Cause_Death
	PX660702021202	If deceased, cause of death	N/A
PX660702_FamilyHistory_Psychosis_Figs_Id
	PX660702020300	What is the family ID number?	N/A
PX660702_FamilyHistory_Psychosis_Figs_Informant_Id
	PX660702020500	What is the Informant's ID number?	N/A
PX660702_FamilyHistory_Psychosis_Figs_Informant_Name
	PX660702020400	What is the first, middle, and last name of more the Informant? show less	N/A
PX660702_FamilyHistory_Psychosis_Figs_Interview_Date
	PX660702020100	What's the interview date?	N/A
PX660702_FamilyHistory_Psychosis_Figs_LastKnown_Age
	PX660702021100	Age when subject last seen or known about, or died	N/A
PX660702_FamilyHistory_Psychosis_Figs_LastKnown_Date
	PX660702021201	Year when subject last seen or known about, more or died show less	N/A
PX660702_FamilyHistory_Psychosis_Figs_LastName
	PX660702020200	What is the family last name?	N/A
PX660702_FamilyHistory_Psychosis_Figs_Relationship
	PX660702020800	What is the subject's relationship to the more Informant? show less	N/A
PX660702_FamilyHistory_Psychosis_Figs_Subject_Birthdate
	PX660702020900	What is the birthdate of the person described?	N/A
PX660702_FamilyHistory_Psychosis_Figs_Subject_Id
	PX660702020700	What is the ID number of the person being more described? show less	N/A
PX660702_FamilyHistory_Psychosis_Figs_Subject_Living
	PX660702021000	Is person described living?	N/A
PX660702_FamilyHistory_Psychosis_Figs_Subject_Name
	PX660702020600	What is the first, middle, and last name of more the person being described? show less	N/A
PX660702_FamilyHistory_Psychosis_Figs_Suicide
	PX660702021203	Did the subject commit suicide?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Adopted
	PX660702011000	Was anyone adopted?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Behavior
	PX660702012500	(Did anyone) seem odd or eccentric in more behavior or appearance? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Delusion
	PX660702012600	(Was anyone) extremely jealous, or more suspicious, or believe in magic, or see special meanings in things that no one else saw? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Depression
	PX660702011500	Feel very low for a couple of weeks or more, more or have a diagnosis of depression? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Hospitalization
	PX660702012200	(Was anyone) hospitalized for psychiatric more problems, or for drug or alcohol problems? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Id
	PX660702010700	What is the family ID number?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Informant_Id
	PX660702010900	What is the Informant's ID number?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Informant_Name
	PX660702010800	What is the first, middle, and last name of more the Informant? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Inherited_Disease
	PX660702012300	Have inherited medical diseases such as more Huntington's disease or seizure disorder or any other disorders of the brain or nervous system? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Interview_Date
	PX660702010500	What's the interview date?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_LastName
	PX660702010600	What is the family last name?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Loner
	PX660702012400	(Did anyone) have few friends, or seem to be more a loner? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Mania
	PX660702011700	Seem overexcited (or manic) day and night, more or have a diagnosis of mania? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Mental_Retardation
	PX660702011100	Was anyone mentally retarded?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Nerves
	PX660702011200	Have problems with their nerves or emotions?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Nerves_Lithium
	PX660702011400	Take lithium?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Nerves_Medication
	PX660702011300	Take medicine or see a doctor for it?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Schizophrenia
	PX660702011900	Have unusual or bizarre behavior, or have a more diagnosis of schizophrenia? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Substance_Abuse
	PX660702012100	Have alcohol or drug use that caused more problems (with health, family, job, or police)? Go to AA or NA, or have treatment for this? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Suicide
	PX660702011600	Attempt or complete suicide?	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Trouble
	PX660702012000	Have trouble with the police, with more completing school, or with keeping a job? show less	N/A
PX660702_FamilyHistory_Psychosis_GeneralScreening_Visions
	PX660702011800	Have visions, hear voices, or have beliefs more that seem strange or unreal? show less	N/A
PX660702_FamilyHistory_Psychosis_Pedigree_Children
	PX660702010400	Does the participant have any children?	N/A
PX660702_FamilyHistory_Psychosis_Pedigree_Siblings
	PX660702010100	Does the participant have any brothers or sisters?	N/A
PX660702_FamilyHistory_Psychosis_Pedigree_Siblings_SamePArents
	PX660702010300	For full biological siblings more (brothers/sisters who have same mother and father as participant), where does the participant fall in birth order? show less	N/A
PX660702_FamilyHistory_Psychosis_Pedigree_Siblings_Yes
	PX660702010200	Do all your siblings have the same mother more and father as you? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Beliefs
	PX660702030600	Code for a single episode (best recalled, more worst episode if possible). What were his/her unusual beliefs or experiences? Specify show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Broadcast_Thoughts
	PX660702031000	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever believe his/her thoughts were broadcast, or that an outside force took away his/her thoughts or put thoughts into his/her head? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Duration
	PX660702032000	(Probe and code YES if mania and/or more depression lasted at least 30% of total duration of illness described above, or medication for it.) show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Duration_Weeks
	PX660702032700	Total illness duration (all episodes, more includes active and prodromal and/or residual symptoms and/or treatment). show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Duration_Years
	PX660702032800	Total illness duration (all episodes, more includes active and prodromal and/or residual symptoms and/or treatment). show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Emotions
	PX660702031700	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever appear to have no emotions, or inappropriate emotions? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Episode
	PX660702031800	How long did the longest of these more experiences last? In weeks show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Episodes
	PX660702032600	Number of episodes (Code 001 if chronic more symptoms and/or treatment since onset): show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Hallucination_Audio
	PX660702031301	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever hear voices or other sounds that were not real? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Hallucination_Describe
	PX660702031302	If Yes, describe	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Hallucination_Other
	PX660702031400	(Code YES if: Voice with content having no more relation to depression or elation, or voice keeping up running commentary on subject's behavior or thoughts, or two or more voices conversing.) show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Hallucination_Sight
	PX660702031200	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever see things that were not really there? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Harm
	PX660702030700	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever believe people were following him/her, or that someone was trying to hurt or poison him/her? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Informant_Id
	PX660702030300	What is the Informant's ID number?	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Informant_Name
	PX660702030200	What is the first, middle, and last name of more the Informant? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Interviewer_Judgement
	PX660702033000	Interviewer judgement on reliability of this more information: show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Interview_Date
	PX660702030100	What's the interview date?	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Medication
	PX660702032100	(Probe and code YES if illness described more above, or medication for it, was ever present for as long as one week, without depression and/or mania.) show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Mindreading
	PX660702030800	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever believe someone was reading his/her mind? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Mood
	PX660702031900	When any (SX above) happened, did he/she more also have the mood disturbance we discussed before, at the same time? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Onset
	PX660702032500	What is the subject's age of onset?	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_OtherBeliefs
	PX660702031101	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever have any other strange or unusual beliefs? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_OtherBeliefs_Describe
	PX660702031102	If Yes, describe	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_OtherDetails
	PX660702032400	Describe details and/or other treatment:	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Outsidecontrol
	PX660702030900	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever believe he/she was under the control of some outside person or power or force? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Physical
	PX660702031600	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever seem to be physically stuck in one position, or move around excitedly without any purpose? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Rate_Impairment
	PX660702032900	Rate and code impairment or incapacitation:	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Speech
	PX660702031501	Code for a single episode (best recalled, more worst episode if possible). Did he/she ever speak in a way that was difficult to make sense of? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Speech_Describe
	PX660702031502	If Yes, describe	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Subject_Id
	PX660702030500	What is the ID number of the person being more described? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Subject_Name
	PX660702030400	What is the first, middle, and last name of more the person being described? show less	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Treatment
	PX660702032301	Code and describe professional treatment:	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Treatment_Ect
	PX660702032304	Describe the treatment received.	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Treatment_Inpatient
	PX660702032302	Describe the treatment received.	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Treatment_Medication
	PX660702032305	Describe the treatment received.	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_Treatment_Outpatient
	PX660702032303	Describe the treatment received.	N/A
PX660702_FamilyHistory_Psychosis_Psychosis_TwoWeeks
	PX660702032200	(Code YES if the above was true for as long more as two weeks.) show less	N/A

Early Psychosis Translational Research

Measure Name

Family History of Mental Illness

Release Date

January 17, 2017

Definition

An interview to collect family psychiatric information of a person with a mental illness.

Purpose

This measure can be used to characterize the diagnoses in first- and second-degree biological relatives of a person with a major mental illness. Family history in close relatives allows an assessment of genetic susceptibility and may be seen as a psychosocial measure of family burden of illness.

Keywords

early psychosis, Family History, relatives, pedigree, symptom checklist, extended family, bilineal, extender, pointer, depression, mania, alcohol/drug abuse, psychosis, paranoid/schizoid/schizotypal personality, Schizophrenia, bipolar, Family Interview for Genetic Studies, FIGS, National Institute of Mental Health, NIMH

Measure Protocols

Protocol ID	Protocol Name
660701	Family History - Multiple Mental Disorders
660702	Family History - Psychosis

Publications

There are no publications listed for this protocol.

Protocol - Family History - Psychosis

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