Protocol - Overactive Bladder Symptoms and Quality of Life
Description
The Overactive Bladder Short Form Questionnaire (OAB-q SF) is a self-administered questionnaire containing 19 items that assess a participant’s experience with overactive bladder over the past four weeks. Each item is rated on a Likert-style scale from 1 (Not at all) to 6 (A very great deal). Scores from individual items are added together to get a final score ranging from 19 to 114. This protocol was validated in patients aged 18 and over and used in patients with sickle cell disease.
Specific Instructions
The Sickle Cell Disease Genitourinary Working Group notes some questions in this assessment are sensitive. Investigators should provide a private space for completing assessments and to be prepared to offer appropriate support.
Availability
Protocol
Overactive Bladder Short Form Questionnaire (OAB-q SF)
Part A. Symptom Bother
This questionnaire asks about how much you have been bothered by selected bladder symptoms during the past 4 weeks. Please place a ✓ or x in the box that best describes the extent to which you were bothered by each symptom during the past four weeks. There are no right or wrong answers. Please be sure to answer every question.
| During the past 4 weeks, how bothered were you by . . . | Not at all | A little bit | Some- what | Quite a bit | A great deal | A very great deal |
| 1. An uncomfortable urge to urinate? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 2. A sudden urge to urinate with little or no warning? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 3. Accidental loss of small amounts of urine? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 4. Nighttime urination? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 5. Waking up at night because you had to urinate? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 6. Urine loss associated with a strong desire to urinate? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
Part B. Health Related Quality of Life
The previous questions asked about your feelings about individual bladder symptoms. For the following questions, please think about your overall bladder symptoms in the past four weeks and how these symptoms have affected your life. Please answer each question about how often you have felt this way to the best of your ability. Please place a ✓ or x in the box that best answers each question.
| During the past week, how often have your bladder symptoms . . . | None of the time | A little of the time | Some of the time | A good bit of the time | Most of the time | All of the time |
| 1. Caused you to plan “escape routes” to restrooms in public places? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 2. Made you feel like there is something wrong with you? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 3. Interfered with your ability to get a good night’s rest? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 4. Made you frustrated or annoyed about the amount of time you spend in the restroom? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 5. Made you avoid activities away from restrooms (i.e., walks, running, hiking)? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 6. Awakened you during sleep? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 7. Caused you to decrease your physical activities (exercising, sports, etc.)? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 8. Caused you to have problems with your partner or spouse? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 9. Made you uncomfortable while traveling with others because of needing to stop for a restroom? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 10. Affected your relationships with family and friends? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 11. Interfered with getting the amount of sleep you needed? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 12. Caused you embarrassment? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
| 13. Caused you to locate the closest restroom as soon as you arrive at a place you have never been? | [ ] 1 | [ ] 2 | [ ] 3 | [ ] 4 | [ ] 5 | [ ] 6 |
Scoring
Symptom Bother Scale:
To score the Symptom Bother scale, sum items 1–6 from part A.
Lowest possible raw score: 6
Highest possible raw score: 36
Possible raw score range: 30
A transformed symptom severity score can be obtained according to the following formula:
| Transformed Symptom Severity Score: | Actual raw score - lowest possible raw score |
| Possible raw score range |
Health Related Quality of Life (HRQL) Scale:
To score the HRQL scale, sum items 1–13 from part B.
Lowest possible raw score: 13
Highest possible raw score: 78
Possible raw score range: 65
A transformed HRQL score can be obtained according to the following formula:
| Transformed HRQL Score: | Highest possible score - Actual raw score |
| Possible raw score range |
Missing Items. For the subscale analyses, if <50% of the scale items are missing, the scale should be retained with the mean scale score of the items present used to impute a score for the missing items. If ≥50% of the items are missing, no scale score should be calculated, the subscale score should be considered missing.
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult, Senior
Participants
Adult
Selection Rationale
The Overactive Bladder Short Form Questionnaire (OAB-q SF) is a well-established self-administered questionnaire that is easy to administer, score and interpret. It has been validated in the general population and in adults and used in patients with sickle cell disease.
Language
English
Standards
| Standard | Name | ID | Source |
|---|
Derived Variables
None
Process and Review
Not applicable
Protocol Name from Source
Overactive Bladder Short Form Questionnaire (OAB-q SF)
Source
Coyne, K. S., Thompson, C. L., Lai, J.-S., & Sexton, C. C. (2015). An overactive bladder symptom and health-related quality of life short-form: Validation of the OAB-q SF. Neurology and Urodynamics, 34(3), 255–263. https://doi.org/10.1002/nau.22559
General References
Anele, U. A., Morrison, B. F., Reid, M. E., Madden, W., Foster, S., & Burnett, A. L. (2016). Overactive bladder in adults with sickle cell disease. Neurology and Urodynamics, 35(5), 642–646. https://doi.org/10.1002/nau.22777
Protocol ID
880101
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Accidental_Loss_Small_Urine | ||||
| PX880101030000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Nighttime_Urination | ||||
| PX880101040000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Sudden_Urge_Urinate | ||||
| PX880101020000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Uncomfortable_Urge_Urinate | ||||
| PX880101010000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Urine_Loss_Desire_Urinate | ||||
| PX880101060000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_4_Weeks_Bothered_Wake_Up_Night_Urinate | ||||
| PX880101050000 | During the past 4 weeks, how bothered were more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Affect_Relationships_Friends_Family | ||||
| PX880101160000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Avoid_Activities_Away_From_Restroom | ||||
| PX880101110000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Awakened_During_Sleep | ||||
| PX880101120000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Caused_Embarrassment | ||||
| PX880101180000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Caused_Locate_Closest_Restroom | ||||
| PX880101190000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Caused_Problems_Partner_Spouse | ||||
| PX880101140000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Decrease_Physical_Activities | ||||
| PX880101130000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Feel_Like_Something_Wrong | ||||
| PX880101080000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Frustrated_Annoyed_Amount_Time_In_Restroom | ||||
| PX880101100000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Interfere_Ability_Good_Night_Rest | ||||
| PX880101090000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Interfere_Getting_Amount_Sleep_Needed | ||||
| PX880101170000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Plan_Escape_Routes | ||||
| PX880101070000 | During the past week, how often have your more | N/A | ||
| PX880101_Overactive_Bladder_Past_Week_Symptoms_Uncomfortable_Traveling_Need_Stop_Restroom | ||||
| PX880101150000 | During the past week, how often have your more | N/A | ||
Measure Name
Overactive Bladder
Release Date
August 15, 2023
Definition
Overactive bladder is a group of symptoms defined by frequent and sudden urges to urinate during the day and night and may include urinary incontinence.
Purpose
Overactive Bladder (OAB) symptoms can impact sleep quality, lead to depression, and negatively impact quality of life, especially in social situations. OAB is associated with neurological conditions, hormone changes, weak pelvic muscles, medications, and certain diseases, such as sickle cell disease and multiple sclerosis.
Keywords
sickle cell disease, quality of life, physical wellness, leak, leakage, urge, bladder, urinary, urology, urogenital
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 880101 | Overactive Bladder Symptoms and Quality of Life |
Publications
There are no publications listed for this protocol.