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Protocol - Perimenopausal Symptoms

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Description

The Greene Climacteric Scale is a twenty-one–item, self-administered questionnaire that captures the symptoms that occur in perimenopause. Each item is rated on a Likert-style scale from “Not at all” (0) to “Extremely” (3). Scores can be derived in six symptom categories: Psychological, Anxiety, Depressed Mood, Vasomotor, Somatic, and Sexuality.

Specific Instructions

The Sickle Cell Disease Genitourinary Working Group notes some questions in this assessment are sensitive. Investigators should provide a private space for completing assessments and to be prepared to offer appropriate support.

Availability

Available

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Protocol

The Greene Climacteric Scale

Please indicate the extent to which you are bothered at the moment by any of these symptoms by placing a tick in the appropriate box.

SYMPTOMS

Not at all

A little

Quite a bit

Extremely

Score 0-3
  1. Heart beating quickly or strongly
  1. Feeling tense or nervous
  1. Difficulty in sleeping
  1. Excitable
  1. Attacks of panic
  1. Difficulty in concentrating
  1. Feeling tired or lacking in energy
  1. Loss of interest in most things
  1. Feeling unhappy or depressed
  1. Crying spells
  1. Irritability
  1. Feeling dizzy or faint
  1. Pressure or tightness in head or body
  1. Parts of body feel numb or tingling
  1. Headaches
  1. Muscle and joint pains
  1. Loss of feeling in hands or feet
  1. Breathing difficulties
  1. Hot flushes
  1. Sweating at night
  1. Loss of interest in sex

Psychological (P), sum items 1-11 = __________
Somatic (S), sum items 12-18 = _____
Vasomotor (V), sum items 19-20 = _____
Anxiety (A), sum items 1-6 = ______
Depressed Mood (D), sum items 7-11 = ______
Sexuality, item 21 = ______

Personnel and Training Required

None

Equipment Needs

None

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Self-administered questionnaire

Lifestage

Adult, Senior

Participants

Adult females who are perimenopausal

Selection Rationale

The Greene Climacteric Scale is a brief, validated, self-administered scale that is easy to use and score.

Language

English

Standards
StandardNameIDSource
Derived Variables

None

Process and Review

Not applicable.

Protocol Name from Source

The Greene Climacteric Scale

Source

Greene J. G. (1998). Constructing a standard climacteric scale. Maturitas, 29(1), 25–31. https://doi.org/10.1016/S0378-5122(98)00025-5

General References

Carpenter, J. S., Sheng, Y., Pike, C., Elomba, C. D., Alwine, J. S., Chen, C. X., & Tisdale, J. E. (2022). Correlates of palpitations during menopause: A scoping review. Women’s Health, 18. https://doi.org/10.1177/17455057221112267

Sourouni, M., Zangger, M., Honermann, L., Foth, D., & Stute, P. (2021). Assessment of the climacteric syndrome: A narrative review. Archives of Gynecology and Obstetrics, 304(4), 855–862. https://doi.org/10.1007/s00404-021-06139-y

Protocol ID

880401

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX880401_Perimenopausal_Symptoms_Attacks_Panic
PX880401050000 Attacks of panic N/A
PX880401_Perimenopausal_Symptoms_Breathing_Difficulties
PX880401180000 Breathing difficulties N/A
PX880401_Perimenopausal_Symptoms_Crying_Spells
PX880401100000 Crying spells N/A
PX880401_Perimenopausal_Symptoms_Difficulty_Concentrating
PX880401060000 Difficulty in concentrating N/A
PX880401_Perimenopausal_Symptoms_Difficulty_Sleeping
PX880401030000 Difficulty in sleeping N/A
PX880401_Perimenopausal_Symptoms_Excitable
PX880401040000 Excitable N/A
PX880401_Perimenopausal_Symptoms_Feel_Dizzy_Faint
PX880401120000 Feeling dizzy or faint N/A
PX880401_Perimenopausal_Symptoms_Feel_Tense_Nervous
PX880401020000 Feeling tense or nervous N/A
PX880401_Perimenopausal_Symptoms_Feel_Tired_Lack_Energy
PX880401070000 Feeling tired or lacking in energy N/A
PX880401_Perimenopausal_Symptoms_Feel_Unhappy_Depressed
PX880401090000 Feeling unhappy or depressed N/A
PX880401_Perimenopausal_Symptoms_Headaches
PX880401150000 Headaches N/A
PX880401_Perimenopausal_Symptoms_Heart_Beating_Quickly_Strongly
PX880401010000 Heart beating quickly or strongly N/A
PX880401_Perimenopausal_Symptoms_Hot_Flushes
PX880401190000 Hot flushes N/A
PX880401_Perimenopausal_Symptoms_Irritability
PX880401110000 Irritability N/A
PX880401_Perimenopausal_Symptoms_Loss_Feeling_Hands_Feet
PX880401170000 Loss of feeling in hands or feet N/A
PX880401_Perimenopausal_Symptoms_Loss_Interest
PX880401080000 Loss of interest in most things N/A
PX880401_Perimenopausal_Symptoms_Loss_Interest_Sex
PX880401210000 Loss of interest in sex N/A
PX880401_Perimenopausal_Symptoms_Muscle_Joint_Pains
PX880401160000 Muscle and joint pains N/A
PX880401_Perimenopausal_Symptoms_Parts_Body_Feel_Numb_Tingling
PX880401140000 Parts of body feel numb or tingling N/A
PX880401_Perimenopausal_Symptoms_Pressure_Tightness_Head_Body
PX880401130000 Pressure or tightness in head or body N/A
PX880401_Perimenopausal_Symptoms_Sweating_Night
PX880401200000 Sweating at night N/A
SCD Genitourinary
Measure Name

Perimenopausal Symptoms

Release Date

August 15, 2023

Definition

Perimenopause is defined as the period before the occurrence of menopause.

Purpose

The onset of menopause is associated with variety of physical symptoms (e.g., sleep disruption, low energy, chills) that can impact quality of life. Certain diseases and conditions, including sickle cell disease and autoimmune diseases, are risk factors for early and premature menopause.

Keywords

climacteric symptoms, menopause, sexual, psychology, anxiety, depression, perimenopause, quality of life

Measure Protocols
Protocol ID Protocol Name
880401 Perimenopausal Symptoms
Publications

There are no publications listed for this protocol.