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Protocol - Thrombosis - Catheter-related

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Description

This protocol from the Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS) study captures age of participant and date of occurrence of catheter-related deep venous thrombosis or pulmonary embolism. The diagnostic method for this is also prompted.

Specific Instructions

The Sickle Cell Disease Pregnancy Working Group recommends that investigators also consider these related protocols: Thromboprophylaxis and Thrombosis - Venous, non-catheter-related. They also suggest that investigators capture the start and stop dates of anticoagulation as well as the trimester. If possible, determine the timing of thrombosis relative to line placement.

Availability

Available

Protocol

Thrombosis – Catheter-related

Age at event (Catheter-related thrombosis): ______________

CATHETER RELATED THROMBOSIS:

Year: ________________

Site: _________________

Diagnostic method:

[ ] Doppler ultrasound

[ ] V/Q perfusion scan

[ ] CT pulmonary angiogram

Personnel and Training Required

Personnel should be trained in medical record abstraction.

Equipment Needs

None

Requirements
Requirement CategoryRequired
Major equipment No
Specialized training No
Specialized requirements for biospecimen collection No
Average time of greater than 15 minutes in an unaffected individual No
Mode of Administration

Medical record abstraction

Lifestage

Child, Adolescent, Adult, Pregnancy

Participants

Children and adults with sickle cell disease.

Selection Rationale

These questions from the Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS) study have been used in participants with sickle cell disease and may be collected from the participant or abstracted from the medical record.

Language

English

Standards
StandardNameIDSource
Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Prophylactic Anticoagulation and central Venous access device-related thromboembolism In adult Sickle cell patients (PAVIS)

Source

Forté, S., De Luna, G., Abdulrehman, J., Fadiga, N., Pestrin, O., Pham Hung dAlexandry dOrengiani, A. L., Aneke, J. C., Guillet, H., Budhram, D., Habibi, A., Ward, R., Bartolucci, P., & Kuo, K. H. M. (2022). Thromboprophylaxis Reduced Venous Thromboembolism in Sickle Cell Patients with Central Venous Access Devices: A Retrospective Cohort Study. Journal of clinical medicine, 11(5), 1193. https://doi.org/10.3390/jcm11051193

General References

Seaman, C. D., Yabes, J., Li, J., Moore, C. G., & Ragni, M. V. (2014). Venous thromboembolism in pregnant women with sickle cell disease: a retrospective database analysis. Thrombosis research, 134(6), 1249?1252. https://doi.org/10.1016/j.thromres.2014.09.037

Protocol ID

890201

Variables
Export Variables
Variable Name Variable IDVariable DescriptiondbGaP Mapping
PX890201_Thrombosis_Catheter_Related_Age
PX890201010000 Age at event (Catheter-related thrombosis): more
______________ show less
N/A
PX890201_Thrombosis_Catheter_Related_Method
PX890201040000 Diagnostic method: N/A
PX890201_Thrombosis_Catheter_Related_Site
PX890201030000 Site: _________________ N/A
PX890201_Thrombosis_Catheter_Related_Year
PX890201020000 Year: ________________ N/A
SCD Pregnancy
Measure Name

Thrombosis

Release Date

August 5, 2024

Definition

Thrombosis is a blockage within a vessel (artery or vein), caused by a blood clot.

Purpose

Participants with certain inherited and acquired blood disorders, including sickle cell disease, have an overall increased risk of developing thrombosis. Additionally, certain acquired factors, such as pregnancy and central line placement, also increase the risk of thrombosis. 

Keywords

Thrombosis, blood clot, deep vein thrombosis (DVT), pulmonary embolism, venous thromboembolism (PE)

Measure Protocols
Protocol ID Protocol Name
890201 Thrombosis - Catheter-related
890202 Thrombosis - Venous - non-catheter-related
Publications

There are no publications listed for this protocol.