Protocol - History of Prepubertal Development - Male
- Assessment of Pubertal Development - Teenage Female
- Assessment of Pubertal Development - Teenage Male
Description
Male participants answer questions about the timing of various maturation milestones.
Specific Instructions
In the original protocol (Swan et al., 2003), male questions 1-4 were administered to the partner of a pregnant woman. However, the PhenX Reproductive Health Working Group is recommending this be administered to all men.
The Expert Review Panel recommends that researchers also ask at what age the respondent reached his maximum height (see History of Prepubertal Development - Female)
Availability
Protocol
Think about when the following events happened to you. Was this earlier than most of your friends, around the same time, or later?
1. Your voice changed. Compared to your friends was this:
1[ ]Earlier
2[ ]About the same time
3[ ]Later
4[ ]Don’t know
1a. Your age when this occurred: _______
[ ] Don’t know
2. Your penis started increasing in size
1[ ]Earlier
2[ ]About the same time
3[ ]Later
4[ ]Don’t know
2a. Your age when this occurred: _______
[ ] Don’t know
3. Your testicles started increasing in size
1[ ]Earlier
2[ ]About the same time
3[ ]Later
4[ ]Don’t know
3a. Your age when this occurred: _______
[ ] Don’t know
4. You developed pubic hair
1[ ]Earlier
2[ ]About the same time
3[ ]Later
4[ ]Don’t know
4a. Your age when this occurred: _______
[ ] Don’t know
5. People reach puberty at different ages. Signs of puberty for males include physical changes such as developing pubic or facial hair, or the voice cracking or lowering. Would you say these changes:
1[ ]Have not yet begun (skip to end)
2[ ]Have barely started
3[ ]Are definitely underway
4[ ]Seem completed
6. How old were you when you entered puberty (that is, when these changes began)?
[ ] Enter age ___
Personnel and Training Required
None
Equipment Needs
Pencil and paper for self-administered questions.
If a computer-assisted instrument is used, computer software may be necessary to develop the instrument. The interviewer will require a laptop computer/handheld computer to administer a computer-assisted questionnaire.
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult
Participants
The sample in Swan et al. (2003) (questions 1-4) consisted of males aged 18-53.
The sample of the National Longitudinal Survey of Youth (questions 5-6) consisted of males aged 12-17.
Selection Rationale
The protocols are from well-established studies with questions that have been used for more than a decade.
Language
Chinese, English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| Logical Observation Identifiers Names and Codes (LOINC) | Hx prepubertal devel male proto | 62658-0 | LOINC |
| Human Phenotype Ontology | Puberty and gonadal disorders | HP:0008373 | HPO |
| caDSR Form | PhenX PX100602 - History Of Prepubertal Development Male | 5970791 | caDSR Form |
Derived Variables
None
Process and Review
The Expert Review Panel #5 (ERP 5) reviewed the measures in the Reproductive Health domain.
Guidance from ERP 5 includes:
- Revised descriptions of the measure
Back-compatible: no changes to Data Dictionary.
Previous version in Toolkit archive (link).
Protocol Name from Source
Study for Future Families (SFF) & National Longitudinal Survey of Youth (NLSY)
Source
Swan, S. H., Brazil, C., Drobnis, E. Z., Liu, F., Kruse, R. L., Hatch, M., . . . Overstreet, J. W.; Study for Future Families Research Group. Geographic differences in semen quality of fertile U.S. Males. Environmental Health Perspectives, 111(4), 414-420. Questions 1-4. Questions from the Study for Future Families.
National Longitudinal Survey of Youth. U.S. Department of Labor. Center for Human Resource Research, The Ohio State University. NLSY97 Questionnaire and Interviewer’s Reference Manual Round 2. Question YSAQ2-284 (question 5) and question YSAQ2-285 (question 6).
General References
August, G. P., Grumbach, M. M., & Kaplan, S. L. (1972). Hormonal changes in puberty. 3. Correlation of plasma testosterone, LH, FSH, testicular size, and bone age with male pubertal development. Journal of Clinical Endocrinology and Metabolism, 34(2), 319-326.
Burr, I. M., Sizonenko, P. C., Kaplan, S. L., & Grumbach, M. M. (1970). Hormonal changes in puberty. I. Correlation of serum luteinizing hormone and follicle stimulating hormone with stages of puberty, testicular size, and bone age in normal boys Pediatric Research, 4(1), 25-35.
MacLaughlin, D. T., & Donahoe, P. K. (2004). Sex determination and differentiation. New England Journal of Medicine, 350(4), 367-378.
Marshall, W., & Tanner, J. M. (1970). Variations in the pattern of pubertal changes in boys. Archives of Disease in Childhood, 45, 13-23.
Raivio, T., Falardeau, J., Dwyer, A., Quinton, R., Hayes, F. J., Hughes, V.A., . . . Pitteloud, N. (2007). Reversal of idiopathic hypogonadotropic hypogonadism. New England Journal of Medicine, 357(9), 863-873.
Protocol ID
100602
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX100602_Developed_Pubic_Hair_Age | ||||
| PX100602040200 | What is your age when you developed pubic hair? | N/A | ||
| PX100602_Developed_Pubic_Hair_Age_Coded | ||||
| PX100602040201 | What is your age when you developed pubic hair? | N/A | ||
| PX100602_Developed_Pubic_Hair_Peer_Comparison | ||||
| PX100602040100 | Think about when the following events more | N/A | ||
| PX100602_Penis_Size_Increased_Age | ||||
| PX100602020200 | What is your age when your penis started more | N/A | ||
| PX100602_Penis_Size_Increased_Age_Coded | ||||
| PX100602020201 | What is your age when your penis started more | N/A | ||
| PX100602_Penis_Size_Increased_Peer_Comparison | ||||
| PX100602020100 | Think about when the following events more | N/A | ||
| PX100602_Puberty_Enter_Began_First_Age | ||||
| PX100602060000 | How old were you when you entered puberty more | N/A | ||
| PX100602_Puberty_Reach | ||||
| PX100602050000 | People reach puberty at different ages. more | N/A | ||
| PX100602_Testicles_Size_Increased_Age | ||||
| PX100602030200 | What is your age when your testicles started more | N/A | ||
| PX100602_Testicles_Size_Increased_Age_Coded | ||||
| PX100602030201 | What is your age when your testicles started more | N/A | ||
| PX100602_Testicles_Size_Increased_Peer_Comparison | ||||
| PX100602030100 | Think about when the following events more | N/A | ||
| PX100602_Voice_Changed_Age | ||||
| PX100602010200 | What is your age when your voice changed? | N/A | ||
| PX100602_Voice_Changed_Age_Coded | ||||
| PX100602010201 | What is your age when your voice changed? | N/A | ||
| PX100602_Voice_Changed_Peer_Comparison | ||||
| PX100602010100 | Think about when the following events more | N/A | ||
Measure Name
History of Prepubertal Development
Release Date
February 26, 2010
Definition
Questions to assess how old participants were when they reached puberty.
Purpose
The purpose of these questions is to determine when participants reached puberty. It is important to measure because it is linked to sexual development and maturity.
Keywords
Reproductive health, puberty, Black Women’s Health Study, BWHS, Study for Future Families, SFF, National Longitudinal Survey of Youth, NLSY
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 100601 | History of Prepubertal Development - Female |
| 100602 | History of Prepubertal Development - Male |
Publications
There are no publications listed for this protocol.