Protocol - Acute Subjective Responses to Substances - Retrospective - Tobacco
- Age of Initiation of First Cigarette Use - Adult
- Alcohol - 30-Day Quantity and Frequency
- Alcohol - Age of First Use
- Alcohol - Lifetime Use Disorder
- Alcohol - Maximum Drinks in 24 Hours
- Cigarette Nicotine Dependence
- Tobacco - 30-Day Quantity and Frequency - Adolescent
- Tobacco - 30-Day Quantity and Frequency - Adult
- Tobacco - Age of Initiation of Use - Adolescent
Description
This instrument uses a set of self-administered questions to assess early response to tobacco smoking, and it may also be used for marijuana smoking. Seven items inquire about pleasant and unpleasant experiences and ask respondents if they encountered various effects while smoking a tobacco cigarette for the first time. Pleasurable and unpleasant sensations are rated on a scale ranging from 1 for "none" to 4 for "intense." Pleasurable rush or buzz, relaxation, nausea, cough, and dizziness are checked "yes" or "no," depending on the respondent’s experience.
Specific Instructions
These questions are only asked if a respondent had affirmatively answered one of the questions in the "Tobacco - Smoking Status" measure. This questionnaire provides a qualitative description of the nature of early smoking experiences, so there are no specific scoring instructions.
The Substance Abuse and Addiction Working Group acknowledges that the following questions may gather sensitive information relating to the use of substances and/or illegal conduct. If the information is released, it might be damaging to an individual’s employability, lead to social stigmatization, or lead to other consequences.
Most researchers assure confidentiality as part of their informed consent process, as required by their institutional review boards. Further assurance of confidentiality may be obtained by applying to the National Institutes of Health (NIH) for a Certificate of Confidentiality, which helps researchers protect the privacy of human research participants. The procedures for the Certificate of Confidentiality can be found at the Grants Policy website of NIH: http://grants1.nih.gov/grants/policy/coc/index.htm.
Availability
Protocol
Please rate the extent to which these words describe your feelings the very first time you smoked a cigarette. The number 1 indicates none, and 4 represents intense.
1. While smoking your very first cigarette, did you have pleasurable sensations?
1[ ]None
2[ ]
3[ ]
4[ ]Intense
2. While smoking your very first cigarette, did you have unpleasant sensations?
1[ ]None
2[ ]
3[ ]
4[ ]Intense
Please answer yes or no to the following questions about the very first cigarette you smoked.
3. While smoking your very first cigarette, did you have a pleasurable buzz or rush?
[ ] Yes
[ ] No
4. While smoking your very first cigarette, did you feel relaxed?
[ ] Yes
[ ] No
5. While smoking your very first cigarette, did you feel dizzy?
[ ] Yes
[ ] No
6. While smoking your very first cigarette, did you have nausea?
[ ] Yes
[ ] No
7. While smoking your very first cigarette, did you cough?
[ ] Yes
[ ] No
8. Were you alone the first time you experimented with cigarettes?
[ ] Yes
[ ] No
Personnel and Training Required
None
Equipment Needs
None
Requirements
| Requirement Category | Required |
|---|---|
| Major equipment | No |
| Specialized training | No |
| Specialized requirements for biospecimen collection | No |
| Average time of greater than 15 minutes in an unaffected individual | No |
Mode of Administration
Self-administered questionnaire
Lifestage
Adult, Senior
Participants
Adults aged 18 years and older
Selection Rationale
This adjective checklist has been widely adopted and validated for tobacco use. An adjective checklist is also available for marijuana, but its application is limited as compared to this adjective checklist being recommended for tobacco.
Language
English
Standards
| Standard | Name | ID | Source |
|---|---|---|---|
| Human Phenotype Ontology | Addictive behavior | HP:0030858 | HPO |
| caDSR Form | PhenX PX520201 - Acute Subj Responses To Substretrospectivetobacco | 6217190 | caDSR Form |
Derived Variables
None
Process and Review
The Expert Review Panel #3 (ERP 3) reviewed the measures in Alcohol, Tobacco and Other Substances, and Substance Abuse and Addiction domains.
Guidance from ERP 3 includes:
• No significant changes to measure
Back-compatible: NA no changes to Data Dictionary
Protocol Name from Source
Pomerleau et al, Early experiences with tobacco among women smokers, ex-smokers, and never-smokers, ADDICTION, 1998
Source
Pomerleau, O. F., Pomerleau, C. S., & Namenek, R. J. (1998). Early experiences with tobacco among women smokers, ex-smokers, and never-smokers. Addiction, 93(4), 595-599.
General References
Fergusson, D. M., Horwood, J. L., Lynskey, M. T., & Madden, P. A. (2003). Early reactions to cannabis predict later dependence. Archives of General Psychiatry, 60(10), 1033-1039.
Haberstick, B. C., Ehringer, M. A., & Lessem, J. M. (2011). Dizziness and the genetic influences on subjective experiences to initial cigarette use. Addiction, 106(2), 391-399.
Perkins, K. A., Lerman, C., Coddington, S., & Karelitz, J. L. (2008). Association of retrospective early smoking experiences with prospective sensitivity to nicotine via nasal spray in nonsmokers. Nicotine and Tobacco Research, 10(8), 1335-1345.
Protocol ID
520201
Variables
Export Variables| Variable Name | Variable ID | Variable Description | dbGaP Mapping | |
|---|---|---|---|---|
| PX520201_First_Cigarette_Alone | ||||
| PX520201080000 | Were you alone the first time you more | N/A | ||
| PX520201_First_Cigarette_Buzz_Or_Rush | ||||
| PX520201030000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Cough | ||||
| PX520201070000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Feel_Dizzy | ||||
| PX520201050000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Feel_Relaxed | ||||
| PX520201040000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Nausea | ||||
| PX520201060000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Pleasurable_Sensations | ||||
| PX520201010000 | While smoking your very first cigarette, did more | N/A | ||
| PX520201_First_Cigarette_Unpleasant_Sensations | ||||
| PX520201020000 | While smoking your very first cigarette, did more | N/A | ||
Measure Name
Acute Subjective Responses to Substances - Retrospective
Release Date
February 24, 2012
Definition
Instruments used separately to assess acute subjective response to substances in the past.
Purpose
The purpose of this measure is to assess acute subjective response to substances (namely, tobacco and alcohol) in the past. Although individual researchers have designed and used their own measures to assess effects of other drugs (e.g., opiates, methamphetamine, and cocaine), at the time the measures were selected for inclusion in the Toolkit, this Working Group was unable to identify a retrospective measure for other drugs that was well-established and broadly applicable.
Keywords
Acute Subjective Response to Drugs, Adjective Checklist, Alcoholism, Buzz, dizziness, Early Response, Level of Response, Nausea, Pass Out, Prediction, Relaxation, Rush, SAA, Self-Rating of the Effects of Alcohol, smoking, SRE, Stumbling, Tolerance, Substance-specific Intermediate Phenotypes
Measure Protocols
| Protocol ID | Protocol Name |
|---|---|
| 520201 | Acute Subjective Responses to Substances - Retrospective - Tobacco |
| 520202 | Acute Subjective Responses to Substances - Retrospective - Alcohol |
Publications
There are no publications listed for this protocol.