Protocol - Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Long Form)

Description

This protocol helps better describe and understand the patient experience and recovery of those with confirmed or suspected COVID-19, with a specific emphasis on Long COVID experience especially with gastrointestinal.

Specific Instructions

None

Availability

This protocol is freely available; permission not required for use.

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Protocol

1. Did you experience these symptoms, and when did you experience them?

Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.

[ ] None of the below gastrointestinal issues apply to me

Gastrointestinal Issues

	N/A	Week 1	Week 2	Week 3	Week 4	Month 2	Month 3	Month 4	Month 5
Constipation	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Diarrhea	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Vomiting	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Nausea	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Loss of Appetite	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Abdominal pain	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Lower Esophagus Burning /gastroesophageal reflux / acid reflux	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]

All Other Symptoms - Checkbox

2. Have you experienced any of these symptoms since the start of your COVID-19 illness? (Please choose all options that apply)

Gastrointestinal

[ ] Feeling full quickly when eating

[ ] Abdominal pain

[ ] Hyperactive bowel sensations

[ ] None of the above

Symptom Course

3. How severe were/are your symptoms over the course of the weeks/months?

If you experienced multiple severities for symptoms within the time period, select the most severe within that time period.

	No symptom	Very Mild	Mild	Moderate	Severe	Very Severe
Week 1	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 2	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 3	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 4	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 2	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 3	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 4	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 5	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 6	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 7+	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]

4. Which of these descriptions appropriately describes your experience with relapses, and your symptom course overall? Please select all that apply:

[ ] My relapses happen in a regular pattern (monthly, daily, or weekly).

[ ] My relapses happen in an irregular pattern (randomly).

[ ] My relapses happen in response to a trigger (stress, alcohol, exercise/exertion, etc).

[ ] My relapses are getting shorter/easier over time.

[ ] My relapses are getting longer/harder over time.

[ ] My relapse severity has stayed about the same over time.

[ ] Overall, my symptoms have slowly gotten better over time.

[ ] Overall, my symptoms have stayed about the same over time.

[ ] Overall, my symptoms have slowly worsened over time.

[ ] I got worse rapidly.

[ ] I got better rapidly.

[ ] Other ___________

7. Which of these trigger a relapse or worsening of symptoms? Please select all that apply:

[ ] Stress

[ ] Alcohol

[ ] Caffeine

[ ] Heat

[ ] Period/menstruation

[ ] Week before period/menstruation

[ ] Exercise

[ ] Physical activity

[ ] Mental activity

[ ] Other ___________

Personnel and Training Required

None

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self-administered questionnaire

Lifestage

Adult

Participants

Adults aged 18 years or older

Selection Rationale

PhenX used input from the PhenX Steering Committee to enable rapid response and release of COVID-19 related protocols in the Toolkit.

Language

English, Other languages available at source

Standards

Standard	Name	ID	Source

Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Online Survey on Recovery from COVID-19

Source

University College London. (2022). Online Survey on Recovery from COVID-19, Section “Gastrointestinal Section”.

General References

Neal C. Goldberg, Sabrina Poirier, Allison Kanas, Lisa McCorkell, Carrie Anna McGinn, Yochai Re’em, Kathi Kuehnel, Nina Muirhead, Tahlia Ruschioni, Susan Taylor-Brown & Leonard A. Jason (2022) A new clinical challenge: supporting patients coping with the long-term effects of COVID-19, Fatigue: Biomedicine, Health & Behavior, 10:4, 212-230, DOI: 10.1080/21641846.2022.2128576

Protocol ID

992011

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Abdominal_Pain
	PX992011010700	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Abdominal Pain show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Apetite_Loss
	PX992011010600	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Loss of Appetite show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Constipation
	PX992011010200	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Constipation show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Diarrhea
	PX992011010300	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Diarrhea show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Lower_Esophagus_Burning
	PX992011010800	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Lower Esophagus Burning /gastroesophageal reflux / acid reflux show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Nausea
	PX992011010500	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Nausea show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_None
	PX992011010100	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Gastrointestinal_Issues_Vomiting
	PX992011010400	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. Vomiting show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Other_Covid_Symptoms
	PX992011020000	Have you experienced any of these symptoms more since the start of your COVID-19 illness? (Please choose all options that apply) Gastrointestinal show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Courses_Replase
	PX992011040100	Which of these descriptions appropriately more describes your experience with relapses, and your symptom course overall? Please select all that apply: show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Courses_Replase_Other
	PX992011040200	Which of these descriptions appropriately more describes your experience with relapses, and your symptom course overall? Please select all that apply: Other show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Relapse_Trigger
	PX992011050100	Which of these trigger a relapse or more worsening of symptoms? Please select all that apply: show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Relapse_Trigger_Other
	PX992011050200	Which of these trigger a relapse or more worsening of symptoms? Please select all that apply: Other show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_2
	PX992011030500	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 2 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_3
	PX992011030600	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 3 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_4
	PX992011030700	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 4 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_5
	PX992011030800	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 5 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_6
	PX992011030900	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 6 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Month_7
	PX992011031000	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 7+ show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Week_1
	PX992011030100	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 1 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Week_2
	PX992011030200	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 2 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Week_3
	PX992011030300	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 3 show less	N/A
PX992011_Long_COVID_Symptoms_Gastrointestinal_Long_Symptom_Severity_Week_4
	PX992011030400	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 4 show less	N/A

Long COVID

Measure Name

Long COVID - Symptoms Due to COVID-19

Release Date

March 17, 2023

Definition

This is a measure of an individual’s new or continuing COVID-19 symptoms.

Purpose

Presence of lingering COVID-19 symptoms is a sign of Long COVID, and use of this measure helps with understanding people’s experience with COVID-19 and implications of Long COVID.

Keywords

coronavirus, COVID-19, Gastrointestinal, University College London, UCL

Measure Protocols

Protocol ID	Protocol Name
992001	Long COVID - Symptoms Due to COVID-19 - Screener
992002	Long COVID - Symptoms Due to COVID-19 - Memory
992003	Long COVID - Symptoms Due to COVID-19 - Neurology
992004	Long COVID - Symptoms Due to COVID-19 - Psychological Risk Factors
992005	Long COVID - Symptoms Due to COVID-19 - Speech, Language, and Hearing
992006	Long COVID - Symptoms Due to COVID-19 - Psychiatric (Short Form)
992007	Long COVID - Symptoms Due to COVID-19 - Psychiatric (Long Form)
992008	Long COVID - Symptoms Due to COVID-19 - Temperature Regulation and Cardiovascular
992009	Long COVID - Symptoms Due to COVID-19 - Cardiovascular Symptom Course
992010	Long COVID - Symptoms Due to COVID-19 - Respiratory
992011	Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Long Form)
992012	Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Short Form)
992013	Long COVID - Symptoms Due to COVID-19 - Allergies
992014	Long COVID - Symptoms Due to COVID-19 - Skin and Hair
992015	Long COVID - Symptoms Due to COVID-19 - Ocular (Long Form)
992016	Long COVID - Symptoms Due to COVID-19 - Ocular (Short Form)
992017	Long COVID - Symptoms Due to COVID-19 - Genitourinary
992018	Long COVID - Symptoms Due to COVID-19 - Muscle and Joint
992019	Long COVID - Symptoms Due to COVID-19 - Tooth Pain
992020	Long COVID - Symptoms Due to COVID-19 - Pediatric

Publications

There are no publications listed for this protocol.

Protocol - Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Long Form)

Essential Protocols:

Description

Specific Instructions

Availability

Protocol

Personnel and Training Required

Equipment Needs

Requirements

Mode of Administration

Lifestage

Participants

Selection Rationale

Language

Standards

Derived Variables

Process and Review

Protocol Name from Source

Source

General References

Protocol ID

Variables

Measure Name

Release Date

Definition

Purpose

Keywords

Measure Protocols

Publications