Protocol - Long COVID - Symptoms Due to COVID-19 - Allergies

Description

A self-administered questionnaire to better describe and understand the patient experience and recovery of those with confirmed or suspected COVID-19, with a specific emphasis on Long COVID experience especially with allergies.

Specific Instructions

None

Availability

This protocol is freely available; permission not required for use.

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Protocol

Skin and Allergy Symptoms

1. Did you experience these symptoms, and when did you experience them?

Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.

[ ] None of the below skin and allergy symptoms apply to me

Skin and Allergy Symptoms

	N/A	Week 1	Week 2	Week 3	Week 4	Month 2	Month 3	Month 4	Month 5
Peeling skin	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Petechiae (tiny purple, red, or brown spots on the skin, usually on arms, legs, stomach, buttocks, and occasionally inside mouth or on eyelids)	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
COVID toes (discoloration, swelling, painful, or blistering toes)	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Dermatographia (writing on your skin causes red lines where you scratched)	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
New allergies (food, chemical, environmental, etc)	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Skin rashes	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Other ________	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]

All Other Symptoms - Checkbox

2. Have you experienced any of these symptoms since the start of your COVID-19 illness? (Please choose all options that apply)

Skin and Allergy

[ ] New allergies (food, chemical, environmental, etc)

[ ] Heightened reaction to old allergies

[ ] Itchy skin

[ ] Itchy eyes

[ ] Itchy other ________

[ ] Brittle/discolored nail

[ ] Shingles

[ ] None of the above

Symptom Course

3. How severe were/are your symptoms over the course of the weeks/months?

If you experienced multiple severities for symptoms within the time period, select the most severe within that time period.

	No symptom	Very Mild	Mild	Moderate	Severe	Very Severe
Week 1	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 2	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 3	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Week 4	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 2	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 3	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 4	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 5	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 6	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]
Month 7+	[ ]	[ ]	[ ]	[ ]	[ ]	[ ]

4. Which of these descriptions appropriately describes your experience with relapses, and your symptom course overall? Please select all that apply:

[ ] My relapses happen in a regular pattern (monthly, daily, or weekly).

[ ] My relapses happen in an irregular pattern (randomly).

[ ] My relapses happen in response to a trigger (stress, alcohol, exercise/exertion, etc).

[ ] My relapses are getting shorter/easier over time.

[ ] My relapses are getting longer/harder over time.

[ ] My relapse severity has stayed about the same over time.

[ ] Overall, my symptoms have slowly gotten better over time.

[ ] Overall, my symptoms have stayed about the same over time.

[ ] Overall, my symptoms have slowly worsened over time.

[ ] I got worse rapidly.

[ ] I got better rapidly.

[ ] Other ___________

7. Which of these trigger a relapse or worsening of symptoms? Please select all that apply:

[ ] Stress

[ ] Alcohol

[ ] Caffeine

[ ] Heat

[ ] Period/menstruation

[ ] Week before period/menstruation

[ ] Exercise

[ ] Physical activity

[ ] Mental activity

[ ] Other ___________

Personnel and Training Required

None

Equipment Needs

None

Requirements

Requirement Category	Required
Major equipment	No
Specialized training	No
Specialized requirements for biospecimen collection	No
Average time of greater than 15 minutes in an unaffected individual	No

Mode of Administration

Self-administered questionnaire

Lifestage

Adult, Senior

Participants

Adults aged 18 years or older

Selection Rationale

PhenX used input from the PhenX Steering Committee to enable rapid response and release of COVID-19 related protocols in the Toolkit.

Language

English, Other languages available at source

Standards

Standard	Name	ID	Source

Derived Variables

None

Process and Review

Not Applicable

Protocol Name from Source

Online Survey on Recovery from COVID-19

Source

University College London. (2022). Online Survey on Recovery from COVID-19, Section “Allergies Section”.

General References

Neal C. Goldberg, Sabrina Poirier, Allison Kanas, Lisa McCorkell, Carrie Anna McGinn, Yochai Re’em, Kathi Kuehnel, Nina Muirhead, Tahlia Ruschioni, Susan Taylor-Brown & Leonard A. Jason (2022) A new clinical challenge: supporting patients coping with the long-term effects of COVID-19, Fatigue: Biomedicine, Health & Behavior, 10:4, 212-230, DOI: 10.1080/21641846.2022.2128576

Protocol ID

992013

Variables

Export Variables

Variable Name	Variable ID	Variable Description	dbGaP Mapping
PX992013_Long_COVID_Symptoms_Allergies_Other_Covid_Symptoms
	PX992013040100	Have you experienced any of these symptoms more since the start of your COVID-19 illness?: (Please choose all options that apply) Skin and Allergy show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Other_Covid_Symptoms_Itchy_Other
	PX992013040200	Have you experienced any of these symptoms more since the start of your COVID-19 illness?: (Please choose all options that apply) Skin and Allergy: Itchy other show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_COVID_Toes
	PX992013030400	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: COVID toes (discoloration, swelling, painful, or blistering toes) show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Dermatographia
	PX992013030500	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Dermatographia (writing on your skin causes red lines where you scratched) show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_New_Allergies
	PX992013030600	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: New allergies (food, chemical, environmental, etc) show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_None
	PX992013010100	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set. show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Peeling_Skin
	PX992013010200	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Peeling skin show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Petechiae
	PX992013030300	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Petechiae (tiny purple, red, or brown spots on the skin, usually on arms, legs, stomach, buttocks, and occasionally inside mouth or on eyelids) show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Skin_Other
	PX992013030800	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Other show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Skin_Other_Specify
	PX992013030801	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Other - specify show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Skin_Allergy_Symptoms_Skin_Rashes
	PX992013030700	Did you experience these symptoms, and when more did you experience them? Please mark symptoms for the first 4 weeks, then months (if applicable). Even if you have only experienced these symptoms for part of a week or month, please select it. If you experienced none of the symptoms in a set, select the checkbox (None of the below issues apply to me) above the grouped set.: Skin and Allergy Symptoms: Skin rashes show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Courses_Replase
	PX992013040100	Which of these descriptions appropriately more describes your experience with relapses, and your symptom course overall? Please select all that apply: show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Courses_Replase_Other
	PX992013040200	Which of these descriptions appropriately more describes your experience with relapses, and your symptom course overall? Please select all that apply: Other show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Relapse_Trigger
	PX992013050100	Which of these trigger a relapse or more worsening of symptoms? Please select all that apply: show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Relapse_Trigger_Other
	PX992013050200	Which of these trigger a relapse or more worsening of symptoms? Please select all that apply: Other show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_2
	PX992013030500	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 2 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_3
	PX992013030600	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 3 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_4
	PX992013030700	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 4 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_5
	PX992013030800	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 5 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_6
	PX992013030900	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 6 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Month_7
	PX992013031000	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Month 7+ show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Week_1
	PX992013030100	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 1 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Week_2
	PX992013030200	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 2 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Week_3
	PX992013030300	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 3 show less	N/A
PX992013_Long_COVID_Symptoms_Allergies_Symptom_Severity_Week_4
	PX992013030400	How severe were/are your symptoms over the more course of the weeks/months? If you experienced multiple severities for symptoms within the time period, select the most severe within that time period. Week 4 show less	N/A

Long COVID

Measure Name

Long COVID - Symptoms Due to COVID-19

Release Date

March 17, 2023

Definition

This is a measure of an individual’s new or continuing COVID-19 symptoms.

Purpose

Presence of lingering COVID-19 symptoms is a sign of Long COVID, and use of this measure helps with understanding people’s experience with COVID-19 and implications of Long COVID.

Keywords

coronavirus, COVID-19, Allergies, University College London, UCL, skin

Measure Protocols

Protocol ID	Protocol Name
992001	Long COVID - Symptoms Due to COVID-19 - Screener
992002	Long COVID - Symptoms Due to COVID-19 - Memory
992003	Long COVID - Symptoms Due to COVID-19 - Neurology
992004	Long COVID - Symptoms Due to COVID-19 - Psychological Risk Factors
992005	Long COVID - Symptoms Due to COVID-19 - Speech, Language, and Hearing
992006	Long COVID - Symptoms Due to COVID-19 - Psychiatric (Short Form)
992007	Long COVID - Symptoms Due to COVID-19 - Psychiatric (Long Form)
992008	Long COVID - Symptoms Due to COVID-19 - Temperature Regulation and Cardiovascular
992009	Long COVID - Symptoms Due to COVID-19 - Cardiovascular Symptom Course
992010	Long COVID - Symptoms Due to COVID-19 - Respiratory
992011	Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Long Form)
992012	Long COVID - Symptoms Due to COVID-19 - Gastrointestinal (Short Form)
992013	Long COVID - Symptoms Due to COVID-19 - Allergies
992014	Long COVID - Symptoms Due to COVID-19 - Skin and Hair
992015	Long COVID - Symptoms Due to COVID-19 - Ocular (Long Form)
992016	Long COVID - Symptoms Due to COVID-19 - Ocular (Short Form)
992017	Long COVID - Symptoms Due to COVID-19 - Genitourinary
992018	Long COVID - Symptoms Due to COVID-19 - Muscle and Joint
992019	Long COVID - Symptoms Due to COVID-19 - Tooth Pain
992020	Long COVID - Symptoms Due to COVID-19 - Pediatric

Publications

There are no publications listed for this protocol.

Protocol - Long COVID - Symptoms Due to COVID-19 - Allergies

Essential Protocols:

Description

Specific Instructions

Availability

Protocol

Personnel and Training Required

Equipment Needs

Requirements

Mode of Administration

Lifestage

Participants

Selection Rationale

Language

Standards

Derived Variables

Process and Review

Protocol Name from Source

Source

General References

Protocol ID

Variables

Measure Name

Release Date

Definition

Purpose

Keywords

Measure Protocols

Publications